Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Lysophosphatidylinositol"”.
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Profiling the activity of GPR55 antagonists against recombinant and endogenous GPR55
… ligands and the endogenous lipid, L-α-lysophosphatidylinositol (LPI). GPR55 mRNA is expressed widely throughout the body, particularly in the brain, bone and immune tissue, and is also expressed at high levels in certain types of tumour. Understanding the physiological and pathological …
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GPR55 and N-acyl Amino Acids
… receptor activated by the endogenous lipid, lysophosphatidylinositol (LPI) and is reported as a putative cannabinoid receptor. However GPR55 shares limited homology with the two cloned cannabinoid receptors (CB<sub>1</sub> and CB<sub>2</sub>) but does exhibit some cannabinoid sensitivity. …
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Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences.
… is that of the G-protein coupled receptor-55/Lysophosphatidylinositol (GPR55/LPI). Despite being upregulated in the setting of obesity, the function of GPR55 in obesity and other disease states remains elusive. Therefore, the present study aimed to 1) investigate the role of GPR55 in obesity …
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Studies on the role of GPR55 in cardiovascular physiology and pathophysiology.
… demonstrated that the activation of GPR55 by lysophosphatidylinositol (LPI) in cultured rat neonatal ventricular cardiomyocytes provokes distinct cellular functions that are dependent on the location of GPR55, leading to suggestions that GPR55 may regulate cardiomyocyte function at two …