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Showing 1 to 3 of 3 for “"Lyoprotection"”.
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Investigation of cell-based therapies employing microcapsules and microspheres: encapsulation and controlled release
… and (3) long-term survivability through lyoprotection and osmoadaptation.
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Protection Mechanisms of Excipients on Lactate Dehydrogenase during Freeze-Thawing and Lyophilization
… to explain the mechanisms of labile protein lyoprotection (i.e., stabilization during drying) with excipients. The first is the "single amorphous immobilization hypothesis". This theory proposes that amorphous protein stabilization can only be achieved if another amorphous compound provides …
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Protein stability: Impact of formulation excipients and manufacturing processes in protein-based pharmaceuticals
… is considered a good cryoprotector but has poor lyoprotection properties. Therefore, in the following stage, a 3rd excipient (in a 3-excipients component system) sucrose or trehalose, was introduced into the formulation. The formulation was made up of 20% ArgHCl (LysHCl), and various ratios of …