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Showing 1 to 3 of 3 for “"Lymphoma, B-Cell"”.
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Examining the Role of Regulatory Lymphocytes in a Mouse Model of BCL1 Tumor Dormancy
… is a clinical state where residual tumor cells persist for long periods but do not cause detectable disease. However, tumor regrowth can occur and is accompanied by resistance to treatment and high mortality rates. The mechanisms that mediate tumor dormancy have been studied using the …
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Διάγνωση, πρόγνωση και υποστήριξη θεραπευτικής αγωγής κακοηθών λεμφωμάτων με χρήση τεχνητής νοημοσύνης
Η παρούσα διδακτορική διατριβή έχει ως στόχο τη δημιουργία ενός αποδοτικού μοντέλου για το Λειτουργικό Συνδυασμό Βιο-Ιατρικών δεδομένων (BioMedical data integration). Ξεκινώντας από τη σχεδιαστική ανάλυση της ιατρικής γνώσης και των προβλημάτων που προκύπτουν από τον τρόπο παραγωγής των ιατρικών …
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Pim Kinase Inhibition: Single Agent and Combination Approaches In B-Cell Lymphoma
… kinases are Ser/Thr/Tyr kinases. They modulate B-cell development but become oncoproteins and promote cancer development once overexpressed. Containing three isoforms, Pim-1, -2 and -3 are known to phosphorylate various substrates that regulate transcription, translation, cell cycle, and survival …