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Showing 1 to 3 of 3 for “"Lymphatic valve"”.
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Computational Investigation of Lymphatic Valves and Vessels
The lymphatic system transports macromolecules and fluids throughout the body via contractions of lymphatic vessels. This flow from vessel contractions is regulated by unidirectional lymphatic valves, which allow lymphatic pumping against adverse pressure gradient. Despite the importance of the …
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Tissue-engineered in vitro models for studying lymphatic morphogenesis, pathogenesis, and drug delivery
The lymphatic system is a network consisting of lymphatic vessels and lymphoid organs such as lymph nodes (LNs), which drain excess interstitial fluid and eventually return it to the blood circulatory system via the thoracic duct and subclavian veins. It plays a key role in interstitial fluid …
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Notch Signaling Determines Lymphatic Cell Fate and Regulates Sprouting Lymphangiogenesis
The lymphatic vascular system is necessary for physiological regulation of tissue fluid homeostasis and absorption of dietary fat. Lymphatics also function in the inflammatory response and are involved in pathological conditions such as wound healing and cancer. We show that the Notch signaling …