Global ETD Search
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Showing 1 to 1 of 1 for “"Lymphangioleiomyomatosis"”.
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Therapeutic targeting of DGKA-mediated macropinocytosis in lymphangioleiomyomatosis
BACKGROUND: Lymphangioleiomyomatosis (LAM) is a rare disease characterized by cystic destruction of the lung. It occurs in 80% of people with Tuberous Sclerosis Complex disorder (TSC), a multisystem, autosomal dominant disorder caused by mutations in tumor suppressor genes TSC1 and TSC2. …