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Showing 1 to 2 of 2 for “"Lyconadin A"”.
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An Acyl Radical Cascade Model for the Total Synthesis of Lyconadin A
Lyconadin A (1) is a structurally unique Lycopodium alkaloid with antitumor properties, isolated from the club moss Lycopodium complanatum. We are developing a synthetic route to 1 based on a novel 7-exo-trig/6-exo-trig acyl radical cascade cyclization. The synthesis of model acyl radical cascade …
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Model Studies Towards the Total Synthesis of Lyconadin A via An Acyl Radical Cascade Reaction
Lyconadin A is an alkaloid possessing a unique structure and antitumor activity. The total synthesis of Lyconadin A was proposed via an acyl radical cascade reaction. To investigate the possibility and stereoselectivity of the cascade cyclization, phenyl selenoester 16 was chosen as a model …