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Showing 1 to 3 of 3 for “"Ly49A"”.

  1. Modulation of Ly49A+ Natural Killer Cell Licensing by Major Histocompatibility Complex Class I Alleles

    … of the b, d, k, q, r, and s H2 haplotypes on Ly49A+ NK cells. In ex vivo stimulation assays, some Ly49A-MHC class I haplotype combinations produced an intermediate licensing phenotype, indicating that licensing is not a binary phenomenon. Comparisons of these data with soluble Ly49A tetramer …

    wustl Repository record for Modulation of Ly49A+ Natural Killer Cell Licensing by Major Histocompatibility Complex Class I Alleles (opens in a new tab)

  2. Understanding T cells in type 1 diabetes: a role for c-Maf and characterization of intracellular signaling following engagement of transgenic Ly49A.

    … of T cells by the inhibitory receptor Ly49A. It is not clear why development of protective Th2 cells is poor in T1D. c-Maf transactivates the <italic>IL-4</italic> gene promoting Th2 cell development; therefore abnormalities in c-Maf may contribute to reduced IL-4 production by CD4 …

    siu-theses Repository record for Understanding T cells in type 1 diabetes: a role for c-Maf and characterization of intracellular signaling following engagement of transgenic Ly49A. (opens in a new tab)

  3. The role of NK cells in selectin-dependent tumor suppression

    … injection, or genetically in NK-deficient GrzA-Ly49A transgenic mice, tumor growth is also significantly enhanced.

    mit Repository record for The role of NK cells in selectin-dependent tumor suppression (opens in a new tab)