Global ETD Search

The Immunopathogenesis of HLA B27-associated Spondylarthritis and Acute Anterior Uveitis

Amjadi, ShahriarUNSW, Sydney2016

… the host, triggering an inflammatory response. Lumican is an extracellular molecule that is found in both the eye and joint and has important structural, functional and immunological functions. This study showed that lumican was present in the aqueous humor of eyes in patients with AAU. …

unsw Repository record for The Immunopathogenesis of HLA B27-associated Spondylarthritis and Acute Anterior Uveitis (opens in a new tab)

Germline HOXB13 G84E Mutation Inhibits MEIS1-HOXB13 Driven Tumor Suppression in Prostate Cancer

Mathias Morales (17896130)2025

… reduction in the proteoglycans, Decorin and Lumican. Exogenous addition of Decorin and Lumican reduced growth and migration of PrCa cell lines. These data support the HOXB13-MEIS1 axis in PrCa while providing a foundation for emerging proteoglycan therapies in the CRPC space when AR targeting …

uic

Functions of small leucine-rich repeat proteoglycans in connective tissues

Kalamajski, SebastianDepartment of Experimental Medical Science, Lund Univeristy2008

… requirements. For example, decorin and lumican interact with collagen using their central leucine-rich repeat domains, while fibromodulin makes use of its C-terminal domain. In addition, some SLRPs can inhibit each other's binding to collagen. These differences, together with the …

lund Repository record for Functions of small leucine-rich repeat proteoglycans in connective tissues (opens in a new tab)

Mechanism of Lmx1b-regulated Limb Dorsalization

Feenstra, Jennifer

… together at one genomic locus, Keratocan, Lumican, and Decorin (KLD). To determine whether Lmx1b's regulation of these targets is direct, we used in silico comparative genomic analysis and identified a potential regulatory region with a known Lmx1b binding site (Peak 3). We hypothesized …

loma-linda Repository record for Mechanism of Lmx1b-regulated Limb Dorsalization (opens in a new tab)

Development of a Cellular Model for Morquio A Syndrome

Sierra, Virgen Guadalupe1970

… for rhGALNS using the natural substrate, lumican, of the enzyme.</p>

dominican Repository record for Development of a Cellular Model for Morquio A Syndrome (opens in a new tab)

Sequenz- und Expressionsanalysen kleiner leucin-reicher Proteoglykane bei Patienten mit klassischem Ehlers-Danlos-Syndrom

Pook, Melanie KatharinaUniversität Ulm

ulm-diss Repository record for Sequenz- und Expressionsanalysen kleiner leucin-reicher Proteoglykane bei Patienten mit klassischem Ehlers-Danlos-Syndrom (opens in a new tab)

A quantitative proteomics study of the additive effect of inflammatory cytokines and injurious compression on cartilage damage

Swaminathan, KrishnakumarMassachusetts Institute of Technology2011

… and reduced levels of LTBP1. Also, biglycan and lumican, SLRPs known to be involved in early development are significantly increased, possibly indicating repair attempts. Other SLRPs such as PRELP and chondroadherin are also highly elevated, with one or both injury+cytokine treatments. While MMPs …

mit Repository record for A quantitative proteomics study of the additive effect of inflammatory cytokines and injurious compression on cartilage damage (opens in a new tab)