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Showing 1 to 1 of 1 for “"Low-cost and clinically applicable copy number profiling"”.
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Probabilistic modelling of somatic alterations in bulk tissue and single cells using repeat DNA
… class of structural alterations are somatic copy number alterations (SCNAs). SCNAs have been shown to be major drivers of oncogenesis and are associated with prognosis and response to therapies. Current sequencing and array-based methods that are used to infer SCNAs are cost-prohibitive for …