Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 49 for “"Low density lipoproteins"”.
-
Interaction of Low Density Lipoproteins With Sulfated Polysaccharides
Made available in DSpace on 2014-12-09T14:36:50Z (GMT). No. of bitstreams: 1 6500839.pdf: 2533202 bytes, checksum: add38ac6f27199ed01176244d4bf62e5 (MD5) Previous issue date: 1964
-
The influence of oxidised low density lipoproteins on platelet activation
The oxidation of low density lipoproteins (LDL) may contribute to platelet hyperactivity and thrombotic events in cardiovascular diseases. Although these pathological particles are known to stimulate platelet activation, the exact signalling mechanisms involved are poorly defined. The aim of this …
-
Receptor-mediated endocytosis of low density lipoproteins in aortic endothelial cells
… using dioctadecylindocarbocyanine-labelled lipoproteins and by indirect immunofluorescence microscopy. LDL and acetylated-LDL (AcLDL) were seen bound to the surfaces of subconfluent ECs (at 4°C or at 37°C), as a random distribution of punctate foci. ECs therefore closely resembled …
-
Spontaneous lipid transfers between low density lipoproteins and reconstituted high density lipoproteins
… are important components in the metabolism of low density lipoprotein (LDL) and high density lipoprotein (HDL). Cholesterol spontaneously transfers from LDL to HDL; phospholipid transfer proceeds in the reverse direction. Reconstituted HDL (rHDL) particles were employed in this study. …
-
The Effects of Ketoconazole on the Oxidation of Low Density Lipoproteins by Bovine Aortic Smooth Muscle Cells
… have been shown to oxidatively modify human low-density lipoprotein (LDL). Such oxidized LDL appears to be a significant factor in the etiology of atherosclerosis. This work shows that the azole antifungal drug ketoconazole when added to the culture medium of BASMC inhibits LDL oxidation. …
-
Modification of Low Density Lipoprotein and the Effects of Modified Low Density Lipoproteins on the Endocytic and Secretory Repertoire of the Macrophage
… of the complex interaction between modified low density lipoprotein (LDL) and macrophages in the initiation and development of the atherosclerotic lesion. The first of these concerns the observed biological modification of LDL that leads to its subsequent enhanced uptake by macrophages, and …
-
Effect of High Fat Diets Containing No Cholesterol on the Properties of Rabbit Serum Lipoproteins and the Catabolism of Very Low Density Lipoproteins
… on normal chow, a semisynthetic diet high in safflower oil (SAFF diet), and a semisynthetic diet high in hydrogenated coconut oil (COCO diet) for 9 weeks each.
-
The effect of feeding either egg white, soy and nonfat dairy protein in male subjects on plasma levels of triglycerides and very low density lipoproteins under controlled conditions
… treatments. Plasma total triglyceride and very low density lipoprotein-triglycerides were measured at the beginning, weekly throughout the experimental period, and two weeks after completion of the study. No significant differences existed in serum lipid values between treatment diets nor was …
-
Isolation and Characterization of Blood Lipoproteins From Dairy Cows Fed Control or High Grain Diets (Lactation, Feeding, Lipids)
Lipoproteins from the plasma of three non-lactating Holstein cows were isolated using either preparative ultracentrifugation or gel filtration chromatography. Lipoprotein classes obtained by ultracentrifugation were very low density plus chylomicrons, low density, high density(,1), and high …
-
Development of in vitro Chylomicron Assay Using Caco-2 Cells
… fats are mainly transported by the intestine in lipoproteins: chylomicrons (CMs) and very low density lipoproteins (VLDLs). Unfortunately, studies of the intestinal absorption of dietary fat have been hampered by the lack of an adequate in vitro model system. As an <em>in vitro</em> model Caco-2 …
-
Estrogen replacement in ovariectomized rats fed safflower oil, coconut oil or cocoa butter: the effects on blood lipids and lipoproteins
… 56 days, diets containing 23% coconut oil, safflower oil or cocoa butter. All diets contained 0.5% cholesterol and 0.5% sodium glycotaurocholate. During the last 28 days of feeding, half the ovariectomized rats received, orally, 30 μg of Premarin per day while other rats received the vehicle …
-
Lipoprotein receptors in cultured bovine endothelial cells
Endothelial cells take up and degrade both low density lipoproteins and low density lipoproteins which have been modified by acetylation (AcLDL). In this study, receptors that may be involved in the uptake of these lipoproteins were characterized. The cells used were aortic endothelial cells …
-
The grapefruit flavonoid naringenin as a Hepatitis C virus therapy : efficacy, mechanism and delivery
… (SVR) - HCV RNA in patient plasma drops below detectable levels at week 24 following completion of treatment, which is thought to be indicative of curing the disease - is attainable in only ~50% of patients. In recent years, HCV production has been shown to be inextricably linked to lipid …
-
PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, ATHEROSCLEROSIS AND EXTRACELLULAR VESICLES ¿ EXPERIMENTAL AND CLINICAL EVIDENCE
… inflammatory milieu and uptake of oxidized low-density lipoproteins, whereas the migratory capacity was reduced. When injected into zebrafish embryos, VSMCPCSK9-EVs favoured the recruitment of macrophages toward the site of injection. The results of the present study provide evidence that …
-
Endotelinių mikrodalelių tyrimas pirminėje ląstelių kultūroje /
… in healthy male plasma were investigated using flow cytometry and compared to endothelial microvesicules shed from endothelial cells effected by cyclophilin A in vitro. Healthy subjects were divided into two groups according to cholesterol concentration. Results have shown that in lower …
-
Pathogenesis of experimental tuberculosis in guinea pigs
… drug N-acetylcysteine. We also established that low density lipoproteins were among the host macromolecules that are oxidized during the chronic inflammatory response typical of tuberculosis. Oxidized low density lipoproteins (OxLDL), known to be rich in cholesterol, accumulated in macrophages …
-
Impatto del profilo lipidico sulla malattia aterosclerotica in due differenti coorti di pazienti ad alto rischio cardiovascolare
… hypercholesterolemia [a very increased amount of low-density lipoprotein (LDL) cholesterol], atherogenic dyslipidemia [combined increased amount of LDL cholesterol and tryglicerides (TG)] and pure hypertrygliceridemia (a very increased amount of TG) (2). As previously mentioned, lipid …
-
Einfluß von Pteridinen auf redoxsensitive biochemische Vorgänge
… und die Peroxonitrit-induzierte Oxidation des Low-density Lipoproteins beeinflussen. Dabei zeigt sich Neopterin in beiden Fällen und in allen Konzentrationen als mehr oder weniger starkes Prooxidantium. 7,8-Dihydroneopterin wirkt dagegen üblicherweise als Radikalfänger dosisabhängig …
Page 1 of 3