Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Lou Gehrig's Disease"”.
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Developing Novel Non-Natural Amino Acids as Spectroscopic Reporters of Structure for Peptide Systems
… Mis-folded proteins can lead to some serious diseases such as Alzheimer's disease, Lou Gehrig's disease (ALS), and muscular dystrophy which affect many people. The key to potentially preventing such diseases lies in understanding how and why protein mis-folding occurs and determining ways to …
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Characterizing Factors That Influence Intracellular Thiol-Disulfide Equilibrium
… can cause amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), a common neurodegenerative disease. Our results indicate that hGrx1 uses a monothiol mechanism to preferentially reduce the intramolecular disulfide bond in ALS mutant forms of hSOD1. In addition, both in vivo and in vitro …
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Targeting ALS: A Multi-Cellular Study on the Potential Therapeutic Role of Azole-Based Compounds
… Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disorder that leads to the degeneration of motor neurons, which control voluntary muscle movements such as eating, speaking, and breathing. As these neurons are damaged, voluntary movement …