Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Loop-removal"”.
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Regulatory domains of the Arf GEF Sec7 scaffold autoinhibited and active conformations
… In this conformation the GEF domain displaces a loop in the DCB/HUS domain we refer to as the “D-loop”. Removal of the D-loop results in a modest increase in GEF activity in vitro, and when combined with HDS2 mutations synergistically increases activity and disrupts physiological function …
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Oxidation of trace organic impurities in ultrapure water by UV and ozone
… organic contaminants. Significant synergistic removal effect by the oxidation of the combination of UV light and ozone has been observed on all model compounds except for trichloroethylene, benzoic acid, and methionine. The removal efficiency by the oxidation of the combined treatment is …
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Genetic mechanisms contributing to antimicrobial resistance: gene repression in Mycobacterium, gene transfer in Salmonella, and phage sensitivity in Escherichia
… is overexpressed. Identification of a mRNA stem-loop in the comA promoter region provides a possible gene repression mechanism. We used the MoClo toolkit to assemble comA promoter-luciferase fusions with or without the predicted mRNA secondary structure, and we used site-directed mutagenesis …
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Conformational Entropy in PEPCK Catalysis: Dynamic Motions Critical to Function
… One of these mobile elements, termed the omega-loop due to its architecture, acts like a lid that closes over the active site and has been hypothesized to serve multiple functions during the catalytic cycle. Furthermore, the act of opening and closing the lid domain is thought to be a delicate …