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Showing 1 to 6 of 6 for “"Loop-E"”.

  1. Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor.

    … objective, each amino acid residue in binding loop E was changed to a cysteine and analyzed via electrophysiology and the substituted cysteine accessibility method. It was found that of the 18 loop E mutants analyzed, His142, Ser144, Arg147, and Ser157, all played a role in channel activation …

    uoit Repository record for Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor. (opens in a new tab)

  2. Electromagnetic Form Factors of Hadrons in the Space-Like Region

    … lead us to propose performing these chiral loop e ects at the hadron level which leads to an improvement in a number of low energy observables related to the electromagnetic form factors. The extraction of the pion form factor from pion electroproduction is also studied in detail. …

    adelaide Repository record for Electromagnetic Form Factors of Hadrons in the Space-Like Region (opens in a new tab)

  3. ROLE OF POLO KINASE CDC5 IN DNA DAMAGE PROCESSING AND REPAIR PATHWAY CHOICE.

    … replicativa migrante estende un intermedio D-loop per migliaia di kilobasi. Mutanti cdc5-T238A mostrano un difetto iniziale di BIR, poiché non riescono ad avviare la sintesi del DNA dal D-loop. L’allele cdc5-T238A mostra anche una ridotta presenza del filamento Rad51-ssDNA al sito di …

    milano Repository record for ROLE OF POLO KINASE CDC5 IN DNA DAMAGE PROCESSING AND REPAIR PATHWAY CHOICE. (opens in a new tab)

  4. Functional characterisation of the honeybee Apis mellifera and diamondback moth Plutella xylostella α5 nicotinic acetylcholine receptor identifies a subset of ion channels with unusual pharmacological properties

    … (nAChRs) belong to the superfamily of cysteine-loop ligand-gated ion channels (cysLGICs) and are best known for mediating the fast actions of acetylcholine. These receptors are made up of five subunits belonging to either alpha or non-alpha types that are arranged around a central ion channel. …

    oxford-brookes Repository record for Functional characterisation of the honeybee Apis mellifera and diamondback moth Plutella xylostella α5 nicotinic acetylcholine receptor identifies a subset of ion channels with unusual pharmacological properties (opens in a new tab)

  5. The role of subunit interfaces in the function of nicotinic acetylcholine receptor

    … receptors, the findings suggest that residues in loop B (W176, T177) and loop E (L146 and F144) of β2(+)/β2(-) interface link to the canonical agonist site anticlockwise to β2(+)/β2(-) to modulate maximal agonist responses. Long-range coupling analysis with the modulator β2(+)/β2(-) residues and a …

    oxford-brookes Repository record for The role of subunit interfaces in the function of nicotinic acetylcholine receptor (opens in a new tab)

  6. Molecular mechanism of Trypanosoma brucei Aquaglyceroporin 2

    … filter and/or other locations including loop E and transmembrane helices 4, 5 or 6. The functional state of the purified TbAQP2 reconstituted into liposomes was validated in glycerol uptake/water efflux assays. Radiolabelled pentamidine uptake/binding assays using functional TbAQP2 …

    cambridge Repository record for Molecular mechanism of Trypanosoma brucei Aquaglyceroporin 2 (opens in a new tab)