NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 59 for “"Long-term potentiation (LTP)"”.

  1. 스트레스에 의한 Long-term potentiation (LTP)의 저하를 감소시키는 리튬의 효과

    양, 재진2011

    … structural remodeling. Enhancement of LTP by lithium treatment was reported by an in vitro study. On the other hand, some studies have reported the attenuation of effects of chronic stress situation. In this study, we investigated whether lithium attenuated or prevented the …

    ajou Repository record

  2. Analysis of activity-dependent morphological plasticity of dendritic spines on hippocampal neurons

    Rösch, Jan HaraldLudwig-Maximilians-Universität

    … showed that synaptic activity and especially long-term potentiation (LTP) can modify spine morphology and number, I studied the effect of long-term depression (LTD) on these parameters. I used a local stimulation approach in combination with intracellular recordings and …

    lmu-germany Repository record

  3. EPIGENETIC REGULATION OF MICROGLIAL PHOSPHATIDYLINOSITOL 3-KINASE PATHWAY INVOLVED IN SYNAPTIC PLASTICITY IN RODENTS

    GENEVIEVE SAW TSE JING2020

    … expression, shown to be involved in neuronal LTP. Microglial PI3K was also found to be post-translationally regulated through sumoylation. Electrophysiological recordings in rat hippocampal slices show the involvement of this pathway in long-term potentiation (LTP) in neurons after PI3K and …

    nus Repository record

  4. Direct current stimulation modulates LTP and LTD: activity-dependence and dendritic effects

    Kronberg, Gregory2016

    … To model endogenous plasticity I induced long-term potentiation (LTP) and depression (LTD) at Schaffer collateral synapses in CA1 of rat hippocampal slices. When induction was paired with concurrent DCS, the resulting plasticity was biased towards potentiation, such that LTP was enhanced …

    cuny Repository record

  5. Critical requirements for NMDA receptors in experience-dependent plasticity in the visual cortex

    Chang, Audrey Bing-YuMassachusetts Institute of Technology2007

    … correlates of such plasticity measurements, ie long-term potentiation (LTP) and long-term depression (LTD). Complete removal of NMDA receptors abolishes plasticity, while selective removal of NMDA receptors from distinct circuits in the visual system can reveal a more specific requirement and …

    mit Repository record

  6. CaMKII at a central synapse : α-calcium/calmodium protien kinase II and synaptic plasticity at CA3 Schaffer collateral -- CA1 synapses in the mammalian hippocampus

    Hinds, Heather L., 1969-Massachusetts Institute of Technology2001

    Long term potentiation (LTP) of synaptic transmission at the CA3-CA1 hippocampal synapse is a model synaptic plasticity mechanism that may underlie hippocampal dependent learning and memory. Inhibition of post-synaptic calcium/calmodulin protein kinase II (CaMKII) has been shown to block LTP, and a …

    mit Repository record

  7. Studies on the effect of growth hormone on age-related changes in glutamatergic transmission in the hippocampus

    Molina, DorisWake Forest University2010

    … for the basal synaptic transmission and long term potentiation (LTP) that underlie learning and memory processes. Cognitive function has been reported to decline with age, as reflected by a decline in performance on hippocampal-dependent tests of learning and memory. Parallel to this …

    wfu Repository record

  8. Functional role of NMDA receptor subunit composition in metaplasticity

    Cho, Kathleen K. A. (Kathleen Kyung-Ah)Massachusetts Institute of Technology2009

    … activation, synapses are strengthened (long-term potentiation; LTP) and below this level, synapses are weakened (long-term depression; LTD). Previous work in visual cortex has suggested that the threshold for synaptic modifications is dependent on the recent history of visual experience, …

    mit Repository record

  9. Spatiotemporal Dynamics of CaMKI During Structural Plasticity of Single Dendritic Spines

    Ramnath, Rohit2016

    … regulators of spine structural plasticity and long-term potentiation (LTP) in neurons. CaMKs have promiscuous and overlapping substrate recognition motifs, and are distinguished in their regulatory role based on differences in the spatiotemporal dynamics of activity. While the function and …

    duke Repository record

  10. Molecular mechanisms of synaptic plasticity

    Hwang, HongikMassachusetts Institute of Technology2016

    … increasing neurogranin levels in CAI neurons prolongs the timing window for spike-timing-dependent long-term potentiation (LTP), whereas acute knockdown of neurogranin inhibits the expression of LTP via regulating PP2B activity. We have also found that neurogranin interferes with …

    mit Repository record

  11. Leptin induces a novel form of long-term potentiation at the direct cortical input to hippocampal CA1 synapses

    Luo, XiaoUniversity of Dundee2013

    … NMDA receptors. In particular, leptin induces a long-term (P5-8) or transient (P11-18) depression of synaptic transmission that depends on GluN2B subunit-containing NMDA receptors in juvenile hippocampus, whereas leptin evokes long-term potentiation that depends on GluN2A subunit-containing NMDA …

    dundee Repository record

  12. On the transmission properties of synapses made between granule cells and cerebellar Purkinje cells

    Sims, RobertAston University2003

    In the cerebellar cortex, forms of both long-term depression (LTD) and long-term potentiation (LTP) can be observed at parallel fibre (PF) - Purkinje cell (PC) synapses. A presynaptic variant of cerebellar LTP can be evoked in PCs by raised frequency stimulation (RFS) of parallel fibre at 4-16Hz …

    aston Repository record

  13. Maternal Exposure to Prostaglandin E2 Affects Hippocampal Synaptic Plasticity in Mice Offspring -A Link to Autism Spectrum Disorder

    Abdul Rahiman, Aisha2023

    … day 90-100. I measured Schaffer collateral long-term potentiation (LTP), paired-pulse facilitation (PPF), input/output (I/O) responses, the expression of glutamate receptor components NMDAR subunit 2A, AMPA subunit GluR1, beta-actin, and morphological characteristics such as primary dendrite …

    york Repository record

  14. Regulatory Role of ApoE and Apoer2 in Synaptic Activity: A New Insight into Alzheimer's Disease

    Chen, Ying2010

    … As a result, the ability of Reelin to enhance long-term potentiation (LTP), a form of synaptic plasticity involved in learning and memory formation, is significantly impaired in the hippocampus of mice expressing the human ApoE4 isoform. Taken together, in this thesis, we identified a novel …

    utswmed Repository record

  15. TWO TYPES OF ROS ARE DIFFERENTIALLY INVOLVED IN SPINAL SYNAPTIC PLASTICITY AND MECHANICAL HYPERSENSITIVITY IN NEUROPATHIC PAIN

    Bittar, AliceThe University of Texas Medical Branch at Galveston2019

    … synapses in the dorsal horn express two forms of long term changes in excitability––long term potentiation (LTP) and long term depression (LTD)––which contribute towards increased pain signaling to higher brain regions. Molecular mechanisms involved in the induction and maintenance of spinal LTP …

    utmb Repository record

  16. The role of ionotropic glutamate receptors in chronic central pain after spinal cord injury

    Huaiyu TanThe University of Texas Medical Branch2005

    … CaMKII also has been shown to be a molecular intermediate in both long-term potentiation (LTP) and peripherally induced central sensitization. After contusive SCI, the segments immediately rostral to the injury site show an increase in activated CaMKII. Application of CaMKII inhibitor, KN-93, …

    utmb Repository record

  17. Hippocampal output to neocortex: Examination of the electrophysiological and plastic properties of CA1 projections to the perirhinal cortex

    Kealy, JohnNational University of Ireland Maynooth2009

    … for the transfer of sensory information into long-term storage. This long-term storage is believed to occur in the neocortex and the physiological mechanism underpinning this transfer of information is believed to be long-term changes in synaptic plasticity, namely long-term potentiation (LTP) …

    maynooth Repository record

  18. The role of semaphorin 3A signaling underlying learning and memory formation in the postnatal mouse brain

    Gagnon, Zoe ElisabethBrock University2025

    … occur during learning and memory is known as long-term potentiation (LTP). While some of the intracellular signaling cascades underlying learning and memory have been well-described, key molecular pathways remain less well understood. Semaphorins are a family of secreted and membrane-bound …

    brock Repository record

  19. Role of Intracellular Calcium Stores and Calcium-Permeable AMPARs in Functional and Structural Plasticity in Mouse Hippocampal Slices

    Koek, Laura A2023

    … hypothesis. The formation of short (STM)- or long - term memories (LTM) involve several biochemical changes that either increase or decrease synaptic efficacy. These changes are commonly referred to as Long-term potentiation (LTP) or depression (LTD). LTP can be differentiated into two forms …

    toronto-retro Repository record

  20. MOLECULAR MECHANISM OF HIV-1 TAT INDUCED NEURONAL DYSFUNCTION

    Bagashev, AsenTemple University. Libraries2014

    … many infected with HIV-1 are living much longer. In fact, it is estimated that by 2015, about half of all HIV-positive individuals will be older than 50. Yet those over 50 also progress to AIDS faster than adults in their 20s or 30s. And those in the younger age bracket, even those …

    temple Repository record

Page 1 of 3