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Showing 1 to 2 of 2 for “"Long QT Syndrome Type 3"”.
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The role of the perinexus in Long QT Syndrome Type 3
… voltage-gated sodium channel (Nav1.5) leads to Long QT Syndrome Type 3 (LQT3). LQT3 phenotype can be exacerbated by expanding the perinexus, which is an intercellular nanodomain with high density of Nav1.5 in the intercalated disc. Following this finding, we found that elevating extracellular …