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Showing 1 to 6 of 6 for “"Lon protease"”.
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The role of the N domain in substrate binding, oligomerization, and allosteric regulation of the AAA+ Lon protease
… and often harsh environments. Cells utilize proteases and chaperones to maintain their proteomes. In bacteria, most cytosolic proteolysis is performed by self-compartmentalized AAA+ proteases, which convert the chemical energy of ATP binding and hydrolysis into mechanical work to unfold and …
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Sequenzierung und molekulare Charakterisierung einer Lon-homologen Protease aus Bartonella henselae und heterologe Expression in Escherichia coli
… einer Plasmidgenbank von B. henselae ein 2 kb Klon isoliert werden, dessen Aminosäuresequenz eine starke Homologie zu ATP-abhängigen Lon-Proteasen anderer Bakterienspezies aufwies. Innerhalb der Aminosäuresequenz befinden sich hochkonservierte Bereiche für ein mögliches Walker A- und B-Motiv …
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Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
… chaperones, disaggregases, holdases and proteases. Many years of investigation have led to a partial understanding of how different branches of the protein quality-control network cooperate with each other to accomplish the critical task of refolding or eliminating damaged and aggregated …
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USING ANTISENSE MESSENGER RNA TO DOWNREGULATE LON MEDIATED PROTEOLYSIS IN ESCHERICHIA COLI
… and degradation of the desired protein. In, lon is one of the major proteases responsible for this abnormal protein degradation, including recombinant proteins. Consequently, a variety of antisense strategies have been examined and shown to effectively control endogenous gene expression and …
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Posttranscriptional and posttranslational regulation of virulence in erwinia amylovora
… we characterized the molecular mechanism of Lon protease-mediated virulence regulation. Mutation of the lon gene caused the amylovoran overproduction, the increased T3SS expression and the non-motile phenotype. In the absence of Lon, abundance and stability of the HrpS/HrpA and RcsA proteins …
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MUTACIN IV PRODUCTION IN STREPTOCOCCUS MUTANS UA159: CHARACTERIZATION, REGULATION, AND MECHANISM OF SELF-IMMUNITY
… etiological agent of dental caries. To colonize successfully in the oral cavity, this organism encounters fierce competition with other oral microbiota and this process is facilitated by ribosomally synthesized small cationic peptides called mutacins (bacteriocins) secreted by S. mutans. …