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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"Lon"”.
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Law's Legitimacy: Lon Fuller in a Consequentialist Frame
<p>This thesis argues that Lon Fuller’s approach to jurisprudence offers more important support to the rule of law than has been generally recognized. It argues further that a consequentialist lens allows clearer views of Fuller’s strengths in this regard, despite Fuller’s own resistance to …
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DETERMINATION OF TRACE METALS BY lON-CHROMATOGRAPHY WITH CHEMILUMINESCENCE DETECTION
It is generally considered that the detection step for the determination of trace metals by liquid-chromatographic systems is the weakest area of the analytical procedure. Various post-column reagent systems, for trace metal analysis, based on the highly sensitive luminol-peroxide chemiluminescence …
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Determining the lon-exchange Mechanism of Strontium into a Niobium Doped Titanosilicate
<p>A 25% niobium substituted sitinakite was exchanged with strontium as time resolved X-ray diffraction data was collected. The structural modeling of this data by Rietveld method1 has lead to the determination of the atomic positions of the ions and unit cell parameters as strontium occupancy …
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USING ANTISENSE MESSENGER RNA TO DOWNREGULATE LON MEDIATED PROTEOLYSIS IN ESCHERICHIA COLI
… and degradation of the desired protein. In, lon is one of the major proteases responsible for this abnormal protein degradation, including recombinant proteins. Consequently, a variety of antisense strategies have been examined and shown to effectively control endogenous gene expression and …
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Genetic analysis and phenotypic characterization of Lon mutants of Escherichia coli K-12
A systematic study of a collection of Lon⁻ mutants has been made in order to determine whether their pleiotropic phenotype is due to mutations affecting one or more genes. A fine structure map of the lon locus was constructed by Pl mediated generalized transduction. The lon⁻ mutations were found to …
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Sequenzierung und molekulare Charakterisierung einer Lon-homologen Protease aus Bartonella henselae und heterologe Expression in Escherichia coli
… einer Plasmidgenbank von B. henselae ein 2 kb Klon isoliert werden, dessen Aminosäuresequenz eine starke Homologie zu ATP-abhängigen Lon-Proteasen anderer Bakterienspezies aufwies. Innerhalb der Aminosäuresequenz befinden sich hochkonservierte Bereiche für ein mögliches Walker A- und B-Motiv …
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Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease
… and degrade aberrant proteins. Mechanoenzymes belonging to the AAA+ (ATPases associated with diverse cellular activities) superfamily are present in all domains of life and harness energy from chemical fuels to perform mechanical work by promoting conformational changes in other biological …
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The role of the N domain in substrate binding, oligomerization, and allosteric regulation of the AAA+ Lon protease
… by degradation tags (degrons). In E. coli, the Lon protease is responsible for the degradation of numerous regulatory proteins, including the cell-division inhibitor SulA, but also recognizes and degrades the majority of misfolded proteins. How Lon recognizes and prioritizes such a vast array of …
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Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
… Here we investigate cooperation between the Lon protease and the IbpA and lbpB small heat-shock protein (sHSP) holdases in the model organism, Escherichia coli. sHSPs are molecular chaperones that bind unfolded proteins and prevent their irreversible aggregation. sHSPs contain a central …
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Posttranscriptional and posttranslational regulation of virulence in erwinia amylovora
… we characterized the molecular mechanism of Lon protease-mediated virulence regulation. Mutation of the lon gene caused the amylovoran overproduction, the increased T3SS expression and the non-motile phenotype. In the absence of Lon, abundance and stability of the HrpS/HrpA and RcsA proteins …
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SciP : a novel inhibitor of CtrA transcriptional activity in Caulobacter crescentus
… to G1 by regulated proteolysis. I identify the Lon as the SciP protease and show that Lon is required for SciP proteolysis in vivo and that E. coli Lon degrades SciP in vitro. Finally I engineer a stable allele of sciP and show SciP proteolysis is critical for proper cell cycle progression.
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Identification of a mutation affecting plasmid establishment in Escherichia coli K-12
… establishment in strain JFSS. One such gene is lon. Other mutations, possibly mapping near his and pyrF may influence the first stage of plasmid establishment in this strain.
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MUTACIN IV PRODUCTION IN STREPTOCOCCUS MUTANS UA159: CHARACTERIZATION, REGULATION, AND MECHANISM OF SELF-IMMUNITY
… etiological agent of dental caries. To colonize successfully in the oral cavity, this organism encounters fierce competition with other oral microbiota and this process is facilitated by ribosomally synthesized small cationic peptides called mutacins (bacteriocins) secreted by S. mutans. …
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Serious and Fatal Injury Risk in Road Departure Crashes with Guardrail
… for computing guardrail length of need (LON) with 'departure corridors' based on real-world road departure trajectories. Due to the current procedure's simplified treatment of road departure geometry, LON recommended by the current procedure becomes very conservative for hazards located …
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Constitutional interpretation.
… of the interpretive theories of H. L. A. Hart, Lon L. Fuller, and Ronald Dworkin.
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Efficient control based on a verified model for an autonomous underwater vehicle : a case study of Autonomous Benthic Explorer
… heave and pitch motions. These motions in the lon,gitudinal plane are particularly important for the basic ABE trajectories of forward flight, depth changes and maneuvers involving both. A scale model of the ABE vehicle was towed to determine the lift/drag relationships to nonzero angles of …
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Petrography of Precambrian iron formation, Pembina County, North Dakota
… located anomalies of 67,500 gammas 1.6 lon east of Akra and 71,500 gammas 4 km east of Hensel, the normal magnetic field in this area being about 60,000 gammas. The rock bodies producing the magnetic anomalies were drilled and examination of diamond drill core showed them to consist of …
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Legality Matters: Crimes Against Humanity and the Legitimacy of the Las Through a Fullerian Lens
… law. In this thesis, I use the theories of Lon L. Fuller and the crimes against humanity prohibition on other inhumane acts to explore the prohibition on retroactive law. The theories of Fuller and the example of crimes against humanity suggest that the prohibition on retroactive law is not …
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Influencia de una mezcla de abonos orgánicos y fertilizantes sintéticos sobre el crecimiento y rendimiento del pipian (Cucurbita argyrosperma Huber), Finca El Plantel, Masaya, 2009
… las variables: Número de hojas verdaderas , lon gitud, diámetro y peso del fruto, nú mero de frutos por hectárea y rendimiento (kg.ha - 1 ) . Se cosechó a partir de los 45 días después de la siembra. La prueba de t student refleja que e stadísticamente el número de h ojas no mostró …
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Defining the role of heparan sulfate proteoglycans in APL-1 function in Caenorhabditis elegans
… Heparin sulfate proteoglycans (HSPGs), such as LON-2 glypican and UNC-52 perlecan, are likely candidates for the ECM proteins that interact and guide sAPL-1. The disruption of APL-1 causes phenotypical changes, including in learning, reproduction, and memory; these defects are enhanced when HSPG …
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