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Showing 1 to 2 of 2 for “"Loewe additivity model"”.

  1. Substandard antimicrobial drugs: detection methods and their contributions to antibiotic resistance

    … or colorimetric signals. A computational model was developed to discover experimental factors that increase the probability of selecting a high affinity aptamer. Among them are: micromolar drug target concentration, high affinity substrate to partition aptamers, and high aptamer library …

    bu Repository record for Substandard antimicrobial drugs: detection methods and their contributions to antibiotic resistance (opens in a new tab)

  2. A Bayesian Approach to Dose-Response Assessment and Drug-Drug Interaction Analysis: Application to In Vitro Studies

    … developed a Bayesian framework for dose-response modeling and drug-drug interaction analysis. First, we developed a hierarchical meta-regression dose-response model that accounts for various sources of variation and uncertainty and allows one to incorporate knowledge from prior studies into the …

    uthsc Repository record for A Bayesian Approach to Dose-Response Assessment and Drug-Drug Interaction Analysis: Application to In Vitro Studies (opens in a new tab)