Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Local field potential"”.
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Assessing Neuronal Synchrony and Brain Function Through Local Field Potential and Spike Analysis
<p>Studies of neuronal network oscillations and rhythmic neuronal synchronization have led to a number of important insights in recent years, giving us a better understanding of the temporal organization of neuronal activity related to essential brain functions like sensory processing and …
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Neural Processing in the Three Layer Turtle Visual Cortex
… We investigate the activity of action potentials as well as the slower local field potential activity.To investigate response properties, we explore spatial properties of receptive fields, temporal properties of spontaneous and evoked activity, response adaptation, and correlations …
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Oxygen Polarography in the Awake Macaque: Bridging BOLD fMRI and Electrophysiology
… this new tool we evaluated local field potential and oxygen responses to an engaging visual stimulus in two distinct brain systems. In area V3, a key region in the visual system and representative of stimulus driven sensory cortex, we show increased tissue oxygen and local …
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State space models for isolating neural oscillations
… oscillations of varying frequency and power, in local field potential recordings as well as non-invasive scalp electroencephalograms (EEG). These oscillations are thought to be responsible for coordinating activity across larger brain regions and conveying information across the brain, directing …
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Neural Dynamics in the Developing Piriform Cortex of Awake Rats
… are observed in piriform cortex by recording local field potential (LFP) activity in piriform cortex of awake rats during the first three weeks of life (P0-21). At birth, the piriform LFP exhibits respiration and spindle oscillations in response to odor stimuli. Spindle oscillations increase …
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Time-varying phase relationship between spiking neuronal responses and local field potentials in olfactory processing in manduca sexta
… on the coincidence of their spiking relative to local field potential (LFP) oscillation phase. Using the sphinx moth, Manduca sexta, as a model system, we tested the predictions of the TOM with regard to the trial-to-trial consistency of odor driven oscillations, the phase-locking of action …
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The Impact of Early Life Adversity on Mediodorsal Thalamic-Prefrontal Cortex Maturation
… windows. We found that the pattern of PFC local field potential (LFP) responses to MD train stimulation is developmentally regulated through adolescence and is impacted by ELA exposure. Typically, the pattern of MD-evoked PFC LFP facilitation at 10Hz is dependent on local NMDAR whereas the …
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The temporal and bilateral structure of hippocampal replay
… spatially isolated networks at the level of the local field potential and the information encoded by the two neuronal populations. We found that the neural activity of the two hippocampi was highly correlated in some aspects but not others. As previously reported in the mouse, we found that, in …
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Passive experience-dependent plasticity in mouse primary visual cortex
… in primary visual cortex (V1) of mice. Chronic local field potential (LFP) recordings in layer 4 (L4) of V1 allow for the tracking of visually evoked potentials (VEPs) in response to phase-reversing sinusoidal grating stimuli. As a given visual stimulus becomes familiar to the mouse, the VEP …
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Memory processing of novel experiences in the hippocampus
… of useful information from daily experiences. A potential factor in this selection may be novelty of incoming information. To avoid redundancy in memory storage, the hippocampus may prefer to process novel stimuli. In this dissertation, I used extracellular tetrode recording techniques in freely …
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Temporal Dynamics of Endogenous and Stimulus-Driven Attention: Combined ECoG/fMRI Studies
… while being able to flexibly shift our focus to potentially rewarding or harmful stimuli. Functional brain imaging studies have identified networks of broadly distributed brain regions that are recruited during goal-driven attention (i.e. based on internal expectations or goals) and/or …
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FEAR EXTINCTION AND INFRALIMBIC CORTEX IMPAIRMENT AFTER MILD TRAUMATIC BRAIN INJURY
… gap by combining cued-fear extinction behavior, local field potential recordings, and whole-cell patch-clamp techniques to investigate how mild TBI affects IL network activity and excitability in a mouse model of TBI. Our results demonstrate that mild lateral fluid percussion injury (LFPI) …
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Slipping into Sleep: neurodynamics of alertness transitions in humans and fruit flies
… using both single and multichannel local field potential (LFP) data to show how alertness transitions and sleep modulate different regions of the fly brain. Further, I validate the results by converging evidence from causal manipulations. Finally, I discuss how the mapping of …
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Gamma frequency entrainment attenuates amyloid load and modifies microglia
Gamma oscillations (20-50 Hz), a common local field potential signature in many brain regions, are generated by a resonant circuit between fast-spiking (FS)-parvalbumin (PV)-interneurons and pyramidal cells. Changes in gamma oscillations have been observed in several neurological disorders. …
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Characterizing corticostriatal circuit function during performance of habitual action sequences
… I explored the effect of dopamine depletion on local field potential oscillations in the same region of striatum. My goal was to investigate the interaction between abnormal oscillations caused by dopamine depletion in Parkinson's disease and the functional task-related oscillations that …
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A computational study of the origin of brain oscillations at multiple scales
… of slow oscillatory power (<4 Hz) in the local field potential and an increase of coherence in those bands, suggesting that rs-fMRI connectivity primarily reflects low-frequency neural oscillations. In the second study, I analyzed data from the lab of Nelson Totah to investigate how …
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Cerebellar Coordination of Neuronal and Behavioral Rhythms
… respiratory rhythms and the interactions of local field potential (LFP) oscillations between the lobulus simplex (LS) in the cerebellum, medial prefrontal cortex (mPFC), and dorsal CA1 (dCA1) using multisite in vivo extracellular recordings in freely moving mice. We compared a mouse model of …
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The mouse visually evoked potential : neural correlates and functional applications
The visually evoked potential (VEP) is a local field potential (LFP) evoked in visual cortex in response to visual stimuli. Unlike extracellular single unit recordings, which allow us to probe the function of single spiking cells acutely, the chronic VEP technique gives us insight into ensemble …
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Theta oscillations, timing and cholinergic modulation in the rodent hippocampal circuit
… and spatial memory, and shows rhythmicity in the local field potential and neuronal spiking. Gamma oscillations (>40Hz) are mediatepd by local circuitry and interact with slower theta oscillations (6-10 Hz). Both oscillation frequencies are modulated by cholinergic input from the medial septum. …
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