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Showing 1 to 20 of 37 for “"Liver cirrhosis"”.
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The epithelial-mesenchymal transition of hepatocyte in liver cirrhosis
Liver cirrhosis is characterized by hepatic dysfunction with extensive accumulation of fibrous tissue in the liver. Even though the number of hepatocytes seems to be enough to maintain liver function, hepatic failure is one of the main causes of death in the patients with liver cirrhosis. The role …
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Studies of Prognosis and Nutritional Intervention in Liver Cirrhosis and Liver Transplantation
In patients with chronic liver disease protein-energy malnutrition (PEM) is a common finding. These patients are predisposed to higher rates of in-hospital mortality, hepatic encephalopathy and infectious complications. In cirrhotic patients awaiting orthotopic liver transplantation (OLT), a strong …
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Efficacy of Entecavir in Patients with Hepatitis B virus-Related Decompensated Liver Cirrhosis
"배경/목적: 엔테카비어는 강력한 항 바이러스 효과와 적은 내성 발생률로 만성 B형 간염 환자에서 치료제로 사용되고 있다. 엔테카비어는 비대상 간경변 환자들에게도 안전하게 사용될 수 있는 치료제로 추천되나, 비대상 간경변 환자에서 치료 효과에 대한 연구보고는 드물다. 이에 저자들은 B형 간염에 의한 비대상 간경변 환자를 대상으로 엔테카비어 치료 효과를 알아보고자 하였다. 연구대상 및 방법: 2006년 11월부터 2009년 9월까지 아주대학교 병원에 내원한 만성 B형 간염으로 인한 비대상 간경변 환자 중 6개월 이상 …
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Prediction of Compensated Liver Cirrhosis by Ultrasonography and Routine Blood Tests in Patients with Chronic Viral Hepatitis
BACKGROUND: A liver biopsy is the standard method for the diagnosis of liver cirrhosis in patients with chronic hepatitis. Because the liver biopsy is an invasive method, non-invasive methods have been used to diagnose compensated liver cirrhosis in patients with chronic hepatitis. The current …
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Tracking of Transplanted Mesenchymal Stem Cells Labeled with Fluorescent Magnetic Nanoparticle in Liver Cirrhosis Rat Model with 3T MRI
"Purpose : Liver cirrhosis represents the end stage of chronic liver injury and the only therapeutic option for advanced liver cirrhosis is liver transplantation. As a new therapeutic approach, there have been many studies about the therapeutic effect of transplantation of bone marrow stem cells. …
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Association of Apolipoprotein E Genotypes with Disease Progression in Hepatitis B Virus Infected Patients
… carcinoma (HCC) in patients with chronic liver diseases of various etiologies. Methods: This hospital based case-control study enrolled 183 subjects (47 healthy controls, 50 HBV originated liver cirrhosis, 86 HCC). ApoE genotypes were determined by ApoE genotyping kit, using a PCR method. …
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Factors affecting initial virologic response and emergence of resistant mutants after adefovir treatment in lamivudine resistant chronic hepatitis B patients
… were HBeAg negativity (P=0.04) and presence of liver cirrhosis (P =0.04). Age, sex, pretreatment AST/ALT, pretreatment HBV DNA levels, presence of precore mutation and types of YMDD mutants were not related to IVR duringadefovir treatment. The prevalence of adefovir resistance was 5% at 6 months …
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Inter-alpha-trypsin inhibitor heavy chain H4 as a diagnostic and prognostic indicator in patients with hepatitis B virus-associated hepatocellular carcinoma
… B (CHB), hepatitis B virus (HBV)-related liver cirrhosis, and HBV-related hepatocellular carcinoma (HCC). DESIGN AND METHODS: The study enrolled 300 individuals (50 healthy controls, 50 with CHB, 100 with HBV-associated cirrhosis, and 100 with HBV-associated HCC). Serum ITIH4 levels were …
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Association of HBV DNA and ALT Level with YMDD motif Mutation Type in Lamivudine Resistance for Chronic Hepatitis B
… consecutive patients with chronic hepatitis B or liver cirrhosis who were lamivudine resistant. Patients received 100 mg of lamivudine per day orally for at least 9 months. The duration of lamivudine therapy was from 9 to 94 months(mean 36.2 months). YMDD motif mutants and serum HBV DNA were …
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Effect of autologous macrophage therapy in cirrhosis in response to individual immune reparative pathways: developing a novel therapy
BACKGROUND: Liver cirrhosis is the end stage of any injury process to the liver. Once established it inevitably progresses to complications such as portal hypertension, cancer and death. There is not cure for liver cirrhosis besides liver transplant. We face an unmet demand for treatment of this …
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Toward understanding and mitigating heterogeneity in bone marrow stromal cell cultures for improved therapeutic efficacy
… for indications ranging anywhere from autism to liver cirrhosis to diabetes. They have cited enthusiasm in the cell therapy community not only for their demonstrated differentiation potential toward several lineages, but also due to the anti-inflammatory and immunomodulatory effects of their …
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Oral Cavity: A Biosystems and Potential Source of Infectious Material // Устната кухина – биосистема и възможен източник на инфекциозен материал
… of hepatitis viruses in the development of liver cirrhosis and the proven dependency on gastric cancer and infection with H. pylori.
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Aminoaciduria in childhood
… Cystine-lysinuria Phenylpyruvic oligophrenia Liver cirrhosis and hepatitis Steatorrhoea Galactosaemia Wilson's disease [From p4, Introduction]
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NONCANONICAL PYROPTOSIS PROMOTES NONALCOHOLIC STEATOHEPATITIS VIA LIPID PEROXIDATION AND TRAINED IMMUNITY
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of abnormal liver function in countries with western-style high fat, high cholesterol diets. Liver damage associated with NAFLD may lead to liver cirrhosis, end-stage liver disease and hepatocellular carcinoma (HCC). …
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Measurement of physician hand & patient tissue mechanical impedance
… medical conditions, such as breast cancer and liver cirrhosis, on the basis of tissue impedance without the need for an additional mechanism. Several methods were developed for approximating mechanical impedance using the actuated ultrasound probe, based on the sensors available and models of …
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Quality of Care in Patients with Cirrhosis and Ascites, Hepatic Encephalopathy or Spontaneous Bacterial Peritonitis
… in real world clinical practice in patients with cirrhosis and ascites, hepatic encephalopathy (HE), or spontaneous bacterial peritonitis (SBP).</p> <p>Methods: A retrospective cohort analysis of the UPMC EMR database (2009-2014) with access to full outpatient and limited inpatient data was …
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Caspase-cleaved fragments of cytokeratin-18 as a marker of inflammatory activity in chronic hepatitis B virus infection
… A total of 339 CHB patients who underwent liver biopsy, were included. Serum M30 antigen levels were compared with inactive carriers (n=36), patients with HBeAg- negative hepatitis (n=80), HBeAg-positive hepatitis (n=141) and liver cirrhosis (n=82). RESULTS: Serum M30 antigen levels were …
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Association between Chronic Hepatitis B Virus Infection and Interleukin-10, Tumor Necrosis Factor-α Gene Promoter Polymorphisms
… (72 inactive carriers, 261 chronic hepatitis, 79 liver cirrhosis) and 204 healthy individuals who recovered from HBV infection. We assessed polymorphisms in IL-10 gene promoter (-1082, -819, -592), and TNF-α gene promoter (-308, -238) by single base primer extension assay. The frequency of C/C …
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