Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Liver biology"”.
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Deciphering the roles of scaffold proteins (IQGAP1 and IQGAP2) and xenosensor (CAR) in liver biology
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-08-01
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Alterations in Genomic 5-Hydroxymethylcytosine Level in Hepatocellular Cancer
… on the role of this novel modification in the liver and HCC is needed before it can be therapeutically targeted. To this end, we planned to perform systematic analysis of the role of 5-hmC in liver biology and its aberrations in HCC. In the present study, DNA from primary human HCC and matching …
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Novel Insights Into Normal Aryl Hydrocarbon Receptor Biology Through the Regulation of Stanniocalcin 2
… destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically important, and evidence that the Aryl hydrocarbon Receptor (AhR) can promote cell survival following intrinsic …
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High-throughput approaches to sourcing of human hepatocytes for cell-based therapies
Chronic liver disease affects more than 500 million people worldwide. The only therapy shown to directly prevent mortality is organ transplantation. However, there is growing discrepancy between supply and demand of transplant-grade organs and transplant recipients are subject to a lifetime of …
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Mapping Human Liver Development using Single-Cell Transcriptomics to Reveal Pathways Directing Stem Cell Fates
The liver is an organ with a diversity of essential functions including xenobiotic removal, bile acid production, storage of iron and vitamins, and metabolism of glucose and fatty acids. Hepatocytes, comprising the liver parenchyma, fulfil these functions and form an extensive network with …