Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 174 for “"Liposome"”.
-
Liposome-Mediated DNA Transfer
… second method used artificial insemination with liposome-treated sperm in an effort to produce transgenic animals. The effects of high pressure on cell viability was examined in three cell lines in triplicate using forskolin stimulated cAMP production and trypan blue exclusion. Chinese hamster …
-
Liposome drug delivery systems for anticancer agents
<p>Development of liposome formulation of an amphiphilic anticancer peptide using the ANTS/DPX leakage assay. The effects of lipid composition on the liposomes' resistance to an amphiphilic cyclic peptide c[KS.S.S.KWL W] were studied by the ANTS/DPX leakage assay. One or more unsaturated acyl …
-
DISCRIMINATION OF LIPOSOME-DELIVERED RNA BY MAMMALIAN CELLS.
DISCRIMINATION OF LIPOSOME-DELIVERED RNA BY MAMMALIAN CELLS.
-
Liposome-loaded biosynthetic bacterial cellulose hydrogels for wound management applications
… with traditional drug delivery systems, liposomes have the advantage of controlling drug release thus reducing toxic side effects, in addition to protecting drugs from degradation and clearance. In this study, liposomes were produced via the reverse-phase evaporation (REV) method. The …
-
Development of Liposome Drug Delivery Systems for Anti-Glioma Therapy
… to investigate the potential of ethanol-based proliposomes in generating paclitaxel-loaded liposome delivery in vitro, by employing various phospholipid compositions. Liposomes prepared using ethanol-based proliposome method successfully generated multilamellar vesicles. Three different lipid …
-
Solubility enhancement of poorly water soluble drugs using liposome technology
… was used to dynamically follow the changes in liposome morphology in real time during dehydration thereby providing a alternative assay of liposome formulation and stability. The ESEM analysis clearly demonstrated ibuprofen incorporation enhanced the stability of PC:Chol liposomes.
-
Liposome-anchored local delivery of immunomodulatory agents for tumor therapy
… to these potent molecules. We first prepared liposomes bearing surface-conjugated anti-CD40 and CpG and assessed their therapeutic efficacy and systemic toxicity compared to soluble versions of the same immuno-agonists, injected intratumorally in established solid tumors in mice. …
-
Redox-active Liposome Delivery Agents With Highly Controllable Stimuli-responsive Behavior
Over the last few decades, liposomes have generated a lot of interest as drug delivery vehicles to address the need for providing both increased therapeutic efficacy and decreased systemic exposure, simultaneously. The challenge of increasing drug accumulation at diseased sites, without …
-
Effects of Liposome-Encapsulated TNF-Alpha and Radiation against Colon Cancer
… of TNF-α in sterically stabilized, PEGylated liposomes (STEALTH®). Thus, the overall hypothesis of the research was that the combination of radiation with STEALTH® liposome encapsulated TNF-α (SL-TNF-α) will have greater efficacy and fewer dose-limiting side effects in the LS174T human …
-
Development and Evaluation of Brain Tumor Targeted Liposome Delivery System for Paclitaxel
… this study, I have developed and characterized liposome carriers containing paclitaxel, for targeted delivery to the glioma brain tumors. <br /><br />A liposome drug delivery system specifically aimed at glioma tumors was designed in this study. Liposomes composed of egg phosphotidylchole (EPC), …
-
Cationic liposome-mediated transfection of mammary epithelial cells with AAV-based plasmid DNA
Cationic liposome-mediated delivery of adeno-associated virus (AAV) based plasmid DNA has potential for efficient and safe delivery of DNA into a number of different cell types. The objective of this thesis was to develop techniques for transfecting adult somatic mammary epithelial cells with the …
-
Liposome Encapsulated Manganese Chloride as a Liver Specific Contrast Agent for Magnetic Resonance Imaging
… undertaken to examine the possibility of using a liposome encapsulated paramagnetic ion (Mn$\sp{2+}$) as a contrast agent for magnetic resonance imaging (MRI) of the liver. Previous work with liposomes had shown that liposomes were concentrated in the liver after intravenous injection. Uptake of …
-
A liposome-based ion release impedance sensor for HIV detection at the point-of-care
… strategy for biological detection based on liposome tagging and ion-release impedance spectroscopy. Ion-encapsulating dipalmitoylphosphatidylcholine (DPPC) liposomes can be functionalized with antibodies and are stable in deionized water yet become permeable for ion release upon heating, …
-
Phospholipid Transfer From Vesicles to High Density Lipoproteins, Catalyzed by Human Plasma Phospholipid Transfer Protein (Liposome)
Human plasma phospholipid transfer protein (PLTP) catalyzes the mass transfer of phosphatidylcholine (PC). Partial purification of PLTP yielded proteins with apparent M(,r) = 59,000 and 40,000 by SDS-PAGE. PLTP activity was measured by transfer of ('14)C L-(alpha)-dipalmitoyl PC from egg-PC …
Page 1 of 9