Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Lipid structure"”.
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Hybrid Cyclic/Linear Peptides in a Multi-Component Lipid Structure as a siRNA Delivery System
… cells by crossing the negatively-charged phospholipid cell membrane. The goal of this project was to design hybrid cyclic-linear peptides as siRNA delivery system. We designed and synthesized hybrid cyclic-linear peptides [R5K]W5, [R6K]W6, and [R5K]W7 containing positively-charged arginine …
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Structure and function studies on five homogeneous reconstituted HDL complexes
… transport. HDL consists primarily of phospholipids, cholesterol, cholesterol esters, and apolipoprotein A-I (apo A-I). However, HDL is extremely heterogeneous in size composition and the structure of its lipoprotein components, particularly apo A-I. Due to its inherent structural …
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An investigation of the effect of surfactants on transdermal permeation.
… Cationic and nonionic surfactants also showed structure dependent changes in the permeability which have been discussed in the thesis. The physical techniques proved valuable in detecting changes in the structure of the stratum corneum, especially for changes in lipid structure. Both DSC and …
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Investigating Cholesterol Orientation in Lipid Bilayer by Raman Spectroscopy
… ranging from different sterols to phospholipids to membrane partitioning proteins. While the overall compositions of these various elements are understood in part, how the phospholipid bilayer in cells accommodates the different processes for the copious types of proteins is not fully …
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Effect of aging on metabolic status and hormone responsiveness in the ovary
… additional glucose. We then evaluated membrane lipid order to determine whether animal age affects the membrane structure of granulosa cells. Membrane lipid structure including formation of raft microdomains may affect signaling by receptors involved in reproductive and metabolic functions. …
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Phytoplankton Response to South Louisiana Crude Oil Exposure: Determining Impacts at Individual, Community, Toxin Production, Enzymatic-Activity and Gene-Expression Levels
… signs of oxidative stress and damage in their lipid structure under crude oil exposure. A gene expression study indicated that crude oil does not cause significant difference in the expression levels of selected genes between the control group and samples treated with crude oil. This research …
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Model membrane interactions with ions and peptides at the air/water interface
The interactions between peptides and lipids are of fundamental importance in the functioning of numerous membrane-mediated biochemical processes including antimicrobial peptide action, hormone-receptor interactions, drug bioavailability across the blood-brain barrier and viral fusion processes. …