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Showing 1 to 1 of 1 for “"Lipid phosphate phosphatases"”.
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The Role of Autotaxin in Cancer
… cell growth, without impacting CAF cell numbers. Lipidomic analysis showed IOA-289 and PF8380, another ATX inhibitor, reduce the generation of LPA in 0082T CAF conditioned media. 22:6 LPA was shown to be generated by an ATX independent pathway, and production of 22:6 LPA was upregulated upon ATX …