Global ETD Search
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Showing 1 to 5 of 5 for “"Lipid exchange"”.
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Spontaneous Phosphatidylcholine Exchange Between Vesicles and Micellar Lipid-Apolipoprotein Complexes
The spontaneous exchange of phosphatidylcholine (PC) between model lipoproteins and small unilamellar vesicles was investigated. The model lipoproteins were recombinants of bovine apolipoprotein A-I, egg PC, and cholesterol produced by cholate dialysis. Vesicles contained egg PC and cholesterol in …
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Nuclear magnetic resonance studies on phospholipid membranes using paramagnetic ions
… ions as probes, to the study of phospholipid vesicular membranes and their interactions with membrane active compounds.<br/><br/>Chapter 1 gives a general introduction to the field of biological and model membranes, nmr methods and the use of lanthanide ions. Chapter 11 illustrates and …
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Supramolecular Architectures in Molecular Medicine: Visualizing and Manipulating the Structure of Protein-Lipid Surfaces
… Lipoproteins, a complex of protein and lipid, serve as the primary transporter of cholesterol and other lipids throughout the body. There is a direct correlation between the presence of certain lipoprotein species and the incidence of coronary artery disease. High density lipoproteins …
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THE OPTIMIZATION OF A TIME-RESOLVED, VESICLE-BASED FLUORESCENCE ASSAY FOR THE ACTIVITY OF THE LIPID KINASE PI4K-IIIBETA AND THE EFFECT OF LIPID TRANSFER PROTEINS ON ENZYME ACTIVITY
… (PITPs). In yeast, the PITP Sec14p is known to exchange PI and phosphatidylcholine between lipid bilayers in vitro and proposed to present PI to be phosphorylated by the PI4-kinase Pik1 in a heterotypic ligand exchange fashion. However, the precise mechanism by which this interaction occurs has …
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Incorporation and analysis of bilayer constituents in nanodiscs
Nanodiscs, engineered lipoparticles composed of a lipid bilayer and two surrounding amphipathic proteins, have been utilized to house and solubilize integral membrane proteins and other molecules with large hydrophobic groups which limit their aqueous solubility. In the experiments described …