Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Lipid biology"”.
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Syncytiotrophoblast formation is influenced by genes involved in lipid biology
… the process of trophoblast fusion involving a lipid- signalling event and dynamic membrane rearrangement. Defects altering the structure and abundance of SynT cells in the labyrinth are enriched in embryonic lethal mouse mutants. From these findings, we are interested in understanding the …
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Investigations into the Metabolic Requirements for Lipoic Acid and Lipid Species During the Life Cycle of the Malarial Parasite Plasmodium Berghei
… on a balance of synthesis and scavenging of lipid species for replication. How the parasite creates this balance is particularly important to successfully intervene in transmission of the disease and to generate new chemotherapies to cure infections. This study focuses on two specific aspects …
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The role of PTEN as a PI(3,4)P2 lipid phosphatase in Class I phosphoinositide 3-kinase signalling
… title: The role of PTEN as a PI(3,4)P2 lipid phosphatase in Class I phosphoinositide 3-kinase signalling Abstract Class I phosphoinositide 3-kinases (Class I PI3Ks) are essential players involved in the signalling events in the cell and are critical promoters of cellular growth, survival …
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Growth Hormone and Melanin-Concentrating Hormone receptor in the regulation of energy balance and metabolism
… pancreas islet hyperplasia, and dyslipidemia, but no changes in energy expenditure were observed. Thus, GH is an orexigenic signal in the CNS that leads to obesity and alters insulin and blood lipid profiles. Mice deficient in the gene encoding GHr (GHr KO) were injected in the CNS …
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Characterising the roles of mammalian atlastins in the endoplasmic reticulum and beyond
… of diverse cargo, such as lysosomal hydrolases. Lipidomics and neutral lipid staining revealed higher triglyceride content in neurons lacking ATL1. Moreover, blocking lipolysis degradation led to lipid droplet (LD) accumulation, with significantly more LDs in ATL1 KD neurons. The cellular content …