Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 844 for “"Lineages"”.
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An analysis of human Alu element lineages
The Alu Ya and Yb-lineages are distinct groups of Short INterspersed Elements (SINEs) found exclusively in primates. These lineages are comprised of several distinct subfamilies, which contain elements that are evolutionarily-related because they share common diagnostic mutations. Some of these Alu …
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Regulating Distinct Cell Lineages in the Pancreatic Islet
Type I and type II diabetes mellitus are associated with a loss of functioning insulin-producing β cells in the pancreas. Understanding the mechanism of normal islet and β cell development will be an important step in developing possible treatments for the disease. Nkx2.2 is essential for proper β …
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Contingent and Collateral Figures in Art Institutions: Laboured Feminist Lineages
… of labour, my dissertation considers feminist lineages of artists who reckon with demands of art institutions. Furthermore, my analyses of labour invite self-reflexive meditation about creative labour of research and writing. I introduce the project with a brief sketch of theoretical concerns …
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Retrotransposon mediated genomic fluidity in the human and chimpanzee lineages
… AluYb lineage which is one of most active Alu lineages in the human genome. We suggest that the evolutionary success of Alu elements is driven at least in part by “stealth driver” elements that maintain low retrotransposition activity over extended periods of time and occasionally produce …
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Organizer regeneration and patterning of stem cell lineages in planarians
Planarians are freshwater flatworms capable of whole-body regeneration. Like development, regeneration requires the establishment of tissue patterns and the specification of appropriate cell types. However, regeneration has the additional challenges of performing these tasks in the absence of …
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The genetic analysis of the vulval cell lineages of Caenorhabditis elegans
The cell lineages of the nematode Caenorhabditis elegana are essentially invariant among individuals. We have begun an attempt to understand the genetic specification of one particular cell lineage, that of the hermaphrodite vulva. During vulval development, six equipotentlal cells of the ventral …
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Systematics and Evolution of the Basal Lineages of Therevidae (Insecta: Diptera)
… was to resolve the relationships among the basal lineages of the family Therevidae (Insecta: Diptera) and to test the monophyly of the family and the two basal subfamilies. A chapter on the morphological features of Phycinae and Xestomyzinae was produced to unify the terms used in this study. A …
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Evolutionary Genomics of Dominant Bacterial and Archaeal Lineages in the Ocean
The ocean plays essential roles in Earth's biochemistry. Most of the nutrient transformations that fuel trophic webs in the ocean are mediated by microorganisms. The extent of phylogenetic and metabolic diversity of key culture and uncultured marine microbial clades started to be revealed due to …
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Reconstruction of major male and female lineages of the Strand Muslim community
… to reconstruct the major paternal and maternal lineages of the Muslim population living in the Cape metropolitan area. The Study has shown the ability of molecular genetic tools to give insight into the origins and history of local communities. The study was also used as a point of reference for …
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Geographic distributions and vertebrate host specificity of genetic lineages of Borrelia burgdorferi
Characterizing the diversity of genes associated with virulence and transmission of a pathogen across the pathogen’s distribution can inform our understanding of host infection risk. Borrelia burgdorferi is a vector-borne bacterium that causes Lyme disease in humans and is common in the United …
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Identify the regulatory roles of intestinal secretory cell lineages during gut inflammation
… significant roles of intestinal secretory cell lineages in orchestrating these responses through novel signaling pathways and interactions. The thesis shed light on potential therapeutic targets and suggests novel interventions, including the use of biologics and small molecule drugs, to …
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Sexual differentiation of somatic and germ cell lineages of the mouse gonad
The process of gonadal sex differentiation in mammals remains poorly understood despite the identification of a few key genes such as Sry and Sox9. To further our understanding of gonad organogenesis, a PCR based subtractive hybridization was performed to identify mouse genes that demonstrate …
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Behavioral and genetic characteristics of intestinal cell lineages in health and disease
… rates between the absorptive and secretory lineages (the former is faster), our experimental setup was unable to resolve any possible differences in migratory behaviors. We then turned our attention to quantifying the spatial expression patterns of selected transcripts in the intestinal …
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The Intersections of Play Therapy, the COVID-19 Pandemic, and Lineages of Trauma
As the pandemic unfolded in waves and spikes around the world, there was a push for mental health research on the impact of the COVID-19 pandemic. Due to the overwhelm of mental health care systems, this doctoral work took the shape of a multi-study project that allowed for the exploration of …
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The Derivation of the Myocardial, Epicardial and Endocardial Lineages from Human Pluripotent Stem Cells
… heart is composed of cells from three major lineages: the myocardium, the epicardium and the endocardium. The myocardium is the working muscle and comprises primarily the ventricles and atria. The epicardium represents the outer epithelial layer that surrounds the myocardium and plays a …
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Reconstructing Mutational Lineages In Breast Cancer By Multi-Patient-Targeted Single Cell Dna Sequencing
… of TNBC development, where inferring clonal lineages and mutational chronologies can help characterize the order, timing, and potential impact of single point mutations, such as TP53, in association with early mechanisms of genomic instability, genome doubling, and aneuploid transformation. …
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Novel Insigths on Trade and Genetic Lineages of the Amphi-American Guitarfishes Genus Pseudobatos
<p>Most guitarfishes (65.7%) evaluated by the International Union for Conservation of Nature Red List are classified as threatened and are included in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora. Since the 1930s, these species have been subject …
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A Genomics Approach to Conservation, Systematics, and Phylogeography to Understand Two Lineages of Lamiales
… conservingbiodiversity. This work considers two lineages of Lamiales of very different scales: a tribe with hundreds of species from across the tropics, and a single, rare species that is narrowly endemic and native to Southern California. Among Acanthaceae (ca. 4,000 spp.), Barlerieae (ca. 440 …
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On Quanzhen Daoism and the Longmen Lineage: An Institutional History of Monasteries, Lineages, and Ordinations
… By critically analyzing monasteries, lineages, and texts, this study sheds light on why the notion of lineage is crucial for understanding Qing Daoism. Furthermore, this study challenges the existing understanding of Quanzhen Daoism as a fixed entity that was disconnected from the …
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