Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 264 for “"Limit of detection"”.
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Estimating limit of detection for mass spectrometric analysis methods
Avastamispiir (AP) on üks olulisemaid parameetreid analüüsimeetodite valideerimisel. See näitab madalaimat analüüdi kontsentratsiooni, kus võime hea tõenäosusega öelda, et analüüt on tõesti proovis sees. See parameeter on seega oluline tulemuste õigeks tõlgendamiseks ja analüüsimeetodi …
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Methods for handling missing data due to a limit of detection in longitudinal lognormal data
In animal science, challenge model studies often produce longitudinal data. Many times the lognormal distribution is useful in modeling the data at each time point. Escherichia coli O157 (E. coli O157) studies measure and record the concentration of colonies of the bacteria. There are times when …
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Design, Development, and Validation of an End-User Photo-Thermal Sensing Platform for Rapid Detection and Quantification of Analytes in Fluidic Samples
The ability to detect the presence of specific analytes and quantify their titers in fluidic samples is essential in many industries, spanning from food industries to law enforcement to healthcare and beyond. The existing technologies used for this purpose require the use of specialty equipment by …
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The Development and Validation of a Quantitative Mass Spectrometric Method for the Analysis of Polypeptides in Human Plasma
An assay for the quantitative analysis of the nonapeptide arginine-8-vasopressin has been developed. This utilised sample preparation techniques such as solid phase extraction in conjunction with ultra-high performance liquid chromatography. Methods to improve the limit of detection of AVP have …
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Detecting Copper in Water Using Electrochemiluminescence
The detection of copper ions as Cu(dmp)₂⁺ (dmp=2,9 -dimethyl-1,10-phenanthroline) using electrochemiluminescence (ECL) is reported. Cu(dmp)₂⁺ is formed in situ by reducing Cu₂⁺ ions to Cu⁺ with hydroxylamine hydrochloride and then complexing with the chelating agent dump. ECL was generated by …
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Single molecule methods for clinical biomarker quantification
… recent years there has been an immense expansion of efforts focused on the identification of sensitive and specific molecular indicators of disease. As our understanding of these biomarkers continues to advance, the ability to quantify low abundance biomarkers from small sample sizes has become …
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Direct Quantitative Analysis of Multiple Micrornas
… deregulated in various diseases. Specific sets of deregulated miRNAs, termed miRNA fingerprints, can distinguish diseased from healthy samples. Detecting disease-specific fingerprints could be used in diagnostics, and there are significant efforts toward developing miRNA-detection methods for …
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The Electrochemical Characterisation of Carbon-based Nanomaterials and their Application in the Detection of Heavy Metal Ions
… and investigated for their potential use in the detection of metal ions in aqueous solutions. Firstly, the use of carbon-based nanomaterials commonly used in the construction of electrochemical sensors; multiwalled carbon nanotubes (MWCNTs) and graphene, were characterised using a potassium …
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The insulated gate field effect transistor (IGFET) as a microluminometer
… work presents data concerning the optical nature of the insulated gate field effect transistor (IGFET), how its optical sensitivity relates to its electrical operation, and explores its usefulness as a microluminometer for a chemisensor and biosensor. Although the experiments performed for this …
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An investigation of intraperitoneal procaine penicillin G administration in lactating dairy cows
This study describes the pharmacokinetic profile of procaine penicillin G after intraperitoneal (IP) administration in 8 lactating dairy cows. Procaine pencillin G (PPG, 21,000 IU/kg) was deposited into the abdominal cavity of each cow following an incision in the right paralumbar fossa. Blood and …
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Personal exposure of children to formaldehyde in Perth, Western Australia
… including children. Children spend most of their time indoors at home, however, there are very little data on the contribution of formaldehyde concentrations in homes to personal exposure in children. The principal aim of this cross sectional study was to investigate whether the domestic …
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The use of cyclodextrin template-based metal oxide nanomaterials in the development of electrochemical sensors for phenolic endocrine disruptor compounds
… method in the presence and absence of beta-cyclodextrin β-CD). Such materials were characterized using transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX), attenuated total reflection Fourier transform infrared (ATR-FTIR), X-ray diffraction (XRD), …
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ΜΕΛΕΤΗ ΜΕΘΟΔΟΥ ΠΡΟΣΔΙΟΡΙΣΜΟΥ ΥΠΟΛΕΙΜΜΑΤΩΝ ΖΙΖΑΝΙΟΚΤΟΝΩΝ ΠΑΡΑΓΩΓΩΝ ΤΗΣ ΟΥΡΙΑΣ
A METHOD WAS DEVELOPED FOR THE DETERMINATION OF LINURON AND THREE OF ITS METABOLITES RESIDUES IN POTATOES, USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY, WITH AMINO-BONDED PHASE COLUMN . THE LIMIT OF DETECTION IS 0,01 MG/KG FOR EACH OF THE COMPOUNDS AND METHODS RECOVERY IS 80-102% FOR LINURON AND …
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Development of nanoplasmonic devices for biosensing applications
… sensing systems seek to meet the needs of high-risk patients for portable, convenient, low-cost detection that is also reliable with a sufficient sensitivity and dynamic range for the chosen target. Optical micro- and nanosensors have incredible potential for early stage detection of …
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New Technology Architecture and Strategy for Early Crop Disease Detection
New approaches are required to meet the challenge of devastating disease outbreaks in global agriculture. In particular, systemic, whole-plant methods of early crop disease detection are needed to effectively manage crop diseases that have long asymptomatic period and localized infection, such as …
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Development of diagnostic immunoassays for tularemia and leptospirosis
… tularemia and leptospirosis respectively. Both of these diseases have significant deficits in the diagnostic tools available for efficient early diagnosis, which can result in delayed treatment of these potentially life-threatening infections. Both bacteria are extremely challenging to isolate …
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The Biomedical Application of Conducting Polymers for the Electrochemical Detection of Diseases
… possess electroactive properties in the presence of an electric field. They have potential applications in alternative energy, sensors, display technologies, and biomedicine. In combination with biorecognition molecules like DNA aptamers or antibodies, conducting polymers can be used as biosensing …
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Electric Field Gradient Focusing-UV Detection for Protein Analysis
… the hydrodynamic flow. EFGF has the advantages of concentrating a large volume (100 micro-L) of target proteins without significant band broadening and simultaneously removing unwanted components from the sample. Two types of EFGF devices have been investigated to concentrate and separate …
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Application of Microporous Membranes to Chemiluminescence Analysis
… support the contention that upon pressurization of the reagent reservoir a locally high concentration of reagents is established near the surface of the membrane in the analyte stream. Using reagent flow rates of only a few (mu)L/min, reagent introduction using microporous membranes is shown to …
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Ecological method development for detecting N-nitrosodimethylamine in water using HPLC-PDAD
… chromatographic method with photo-diode array detection (HPLC-PDAD) was investigated to detect sub-parts per billion concentrations of N-nitrosodimethylamine (NDMA) in drinking water and environmental water samples. This presents a practical and “green” option to analytical methods that require …
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