Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Lignocaine"”.
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Reductive metabolism of aliphatic tertiary amine n-oxides.
… amine N-oxides as antiarrhythmic agent prodrugs. Lignocaine was selected as a candidate for prodrug development, because the N-oxide is a non-active, polar derivative of lignocaine and the drug of choice for ventricular arrhythmia, a symptom associated with ischaemic episodes leading to regions of …
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Lignocaine extraction ratio and clearance as an indicator of hypoxic hepatic injury : a study using the in situ and the isolated perfused pig liver
The metabolism of lignocaine to monoethylglycinexylidide has been found useful as an indicator of hepatic function in association with liver transplantation. It has been postulated that this might be due to the common effect of hypoxic damage on liver function and lignocaine metabolism. The aim of …
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The efficacy of intra-arterial lignocaine as an adjuvant analgesic in the management of post-procedural pain following uterineartery embolization for symptomatic uterine fibroids – a comparative study of outcomes
… In particular, the benefit of intra-arterial lignocaine as an adjunctive analgesic following UAE remains uncertain. Method: A single institution retrospective comparative study was undertaken through review of folders of patients who were treated for symptomatic uterine fibroids by UAE between …
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Prevalence and treatment of painful diabetic neuropathy
… quality of life, and treatment employing lignocaine. This first study assessed the prevalence of painful diabetic neuropathy (PDN) and its relationship with various cardiovascular characteristics in diabetes subjects. This was done through an observational study of diabetes subjects in …
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Solubility enhancement of poorly water soluble drugs using liposome technology
… indomethacin, sulindac, mefenamic acid, lignocaine and progesterone to investigate the influence of drugs properties and functional group on liposomal loading. The results show that no defined trend could be obtained linking the drug loading to the different drug properties including …
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Improving pain management for children
… The optimum dose of the amide local anaesthetic, lignocaine, was determined for preventing pain on intravenous injection of propofol in children(Cameron et al., 1992) and this resulted in the widespread adoption of propofol as an induction agent. Several studies of propofol in children were …
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The safety and efficacy of the propofol/ Alfentanil/ Ketamine-bolus technique in midazolam pre-medicated patients undergoing office based plastic or reconstructive surgery
The purpose of this research project was to assess the safety and efficacy of a combination of drugs for conscious sedation in patients undergoing office-based plastic and reconstructive surgery. A pilot study was done to determine the safety of the co-administration of the drugs used in the …