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Showing 1 to 1 of 1 for “"Libraries with insertions and deletions"”.
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In Vitro Evolution of Antibody Affinity using Libraries with Insertions and Deletions
… somatic hypermutation (SHM) leads to antibodies with improved affinity and specificity. Sequence diversification by SHM is mainly achieved by introduction of point substitutions and a small percentage of insertions/deletions (indels). Although the percentage of indels in affinity matured …