Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Lewy Body Dementia"”.
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Lewy Body Dementia and the Role of Inflammation
Background: Lewy body dementia (LBD), consisting of Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), is known to make up more than 15% of dementia cases at autopsy, however the clinical prevalence rate is reported to be much lower at around 5-6%. Difficulties with diagnosis …
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Solid-state NMR structural investigations of alpha-synuclein fibrils derived from Lewy Body dementia brain tissue
… feature of neurodegenerative diseases, including Lewy Body dementia (LBD), Parkinson’s disease (PD), and multiple system atrophy (MSA). Despite this fact, there is currently no way to detect or quantify these fibrils in living patients, which could significantly improve diagnosis and treatment …
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Adapting Behavioral Interventions to Better Support Alzheimer's Disease and Lewy Body Dementia Care Partners Based on Their Unique Needs and Differences
… of individuals with Alzheimer's disease (AD) and Lewy body dementia (LBD) are typically family members or friends. They often experience physical and psychological strain associated with caregiving. Hence, the long-term goal is to improve the physical and psychological health and well-being of …
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Histamine H3 Receptor Heterogeneity in the Central Nervous System in Aging and Dementia.
… and H3 329 isoforms in Parkinson’s disease and Lewy Body Dementia cases, respectively, compared to age-matched controls. We have shown a variety of H3R ligands display differential pharmacological properties at the three hH3R isoforms expressed in HEK 293 cells. Most notably a 5- and 10- fold …
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HISTAMINERGIC H3 AND CANNABINOID CB1 RECEPTORS IN DEMENTIA
… of H3 receptors remain unchanged under vascular dementia or mixed dementia pathology, and may serve as a therapeutic target for cognitive deficits. Measurements of CB1 receptors in postmortem brain samples of Lewy body dementia patients indicate the possible relationship between CB1 loss and …
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Multi-omic Analysis of Neurodegeneration in Alzheimer’s Disease and Related Dementias
… Alzheimer’s Disease (AD), Frontotemporal Dementia (FTD), Lewy Body Dementia (LBD), and Vascular Contributions to Cognitive Impairment and Dementia (VCID). We utilize both single-cell RNA sequencing (scRNA-seq) and single-cell ATAC sequencing (scATAC-seq) to perform a joint analysis of …