Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Lewis X"”.
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Purification and identification of sulfated Lewis X binding proteins in boar sperm
… bind preferentially to glycans containing the Lewis X trisaccharide (LeX) or multi-antennary sialylated N-acetyllactosamine motifs and much less to motifs with terminal mannose. Based on these findings, the aim of this PhD dissertation was to identify sperm molecule/s involved in sperm binding …
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Automated synthesis of the Lewis blood group oligosaccharides
… allowed for the rapid synthesis of three Lewis-type cell surface oligosaccharides. The assembly of the nonasaccharide adenocarcinoma marker Le[superscript]y-Le[superscript]x monosaccharide building blocks was achieved in just 23 hours, while the syntheses of the tumor markers Lewis X, a …
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Sperm release from the oviduct reservoir
… (bi-SiaLN) oligosaccharide and a Lewis X trisaccharide (LeX) to form the sperm reservoir. These glycans are also implicated in the regulation of sperm capacitation by regulating calcium influx and extending sperm life span. My objective was to identify how sperm bound to oviduct …
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Untersuchungen zur funktionellen Bedeutung von Gangliosiden bei der E-Selektin-vermittelten Zell-Zell-Adhäsion
… dar. Als Ligand des E-Selektins wurde das sialyl-Lewis x-Epitop (sLe x; Neu5Ac[alpha]2-3Gal[beta]1-4(Fuc[alpha]1-3)GlcNAc-R) entdeckt. Dieses Epitop wurde sowohl auf Glykoproteinen als auch auf granulocytären Gangliosiden detektiert. Das Arbeitsziel der vorliegenden Arbeit war die Untersuchung der …
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APPROACHES TO IDENTIFY SURFACE PROTEINS OF ANAPLASMA PHAGOCYTOPHILUM DENSE-CORED ORGANISMS AS ADHESINS TO HUMAN P-SELECTIN GLYCOPROTEIN LIGAND-1
… to cause human granulocytic anaplasmosis. Sialyl Lewis x (sLex)-modified P-selectin glycoprotein ligand-1 (PSGL-1) is the confirmed receptor utilized by A. phagocytophilum to bind and invade human neutrophils and myeloid cell lines. As an obligate intracellular pathogen, the binding of A. …
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Analysis and characterisation of human chorionic gonadotropin glycoforms in pregnancy and trophoblastic disorders
… sialylation, sulphation and glycans with Lewis X terminal epitopes. In summary, we have successfully developed a methodology for the detection of a diverse range of N-linked glycans from hCG. These results suggest that this approach can be successfully used for the detection of novel …