Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Lewis Acid Catalyst"”.
-
Study of the reaction of nitriles with dialkyl phosphites for synthesis of a-Amino-bis-phosphonates
… these compounds involved the use of protic acids, which don’t provide ideal conditions for the starting materials containing acid labile functional groups in pharmaceutical compounds. The present study adopts a new synthetic route in which diethyl phosphite addition to the nitrile would be …
-
Chemistry and synthesis of 3(2H)-furanones and 4,5-dihydro analogues: mechanistic investigations and stereochemical control
… 3(2H)-furanones without the involvement of a Lewis acid catalyst. The study, largely involving in situ NMR techniques, identified key features associated with the formation and reaction of the chlorosulfide and chloroselenide intermediates, including operation of the Thorpe-Ingold effect. The …
-
Experimental and Computational Studies on Copper and Hydrobenzoin Derivatives in Catalytic Asymmetric Reactions
… of two hydrobenzoin derivatives as ligands/ catalysts, as well as the attempted synthesis of a third hydrobenzoin derivative. The bis-boronic acid derived from hydrobenzoin was successful as a Lewis acid catalyst in the Bignielli reaction and the Conia ene reaction, but provided only racemic …
-
Trichloroacetimidates As Outstanding Electrophiles for the Carbon-nitrogen, Carbon-oxygen and Carbon-carbon Bonds Formation and Synthetic Studies of Protein Phosphatase-5 (pp5) Small Molecule Inhibitors
… under promoter free conditions, activation by Lewis or Brønsted acid leads to a formation of a carbocation from benzylic trichloroacetimidates. Work described herein makes use of these convenient carbocation precursors for new reactions.Isatin is an ambidentate nucleophile and commonly can be …
-
The Solid Phase Synthesis of M-Phenylene Ethynylene Oligomers and Its Application to the Synthesis of Covalent Molecular Ladders
… polyamine oligomers and utilizing Sc(OTf)3 as a Lewis acid catalyst we were able to form a series of molecular ladders from 3-6 rungs in length. 3 and 4-rung ladders were almost exclusively formed; however a large amount of high molecular weight by-product was formed in the 5 and 6-rung ladder …
-
The synthesis, characterisation and photochemistry of novel organometallic complexes
… or 3-positions using aluminium chloride as the Lewis acid catalyst. Substitution only occurs at the 1'-position, which is thought to be due to deactivation of the methoxy-substituted ring by coordination of the aluminium chloride/acetyl chloride complex by the methoxy group. However, we …
-
Fast flow biopolymer synthesis
… flow peptide synthesizer than incorporates amino acids in as little as 40 seconds each. First, mechanical systems were developed to rapidly switch between the many reagents needed for peptide synthesis while maintaining the proper stoichiometry of all reaction components at all times. Second, …
-
Implementing Solvothermally Synthesized Carbon Nanodots into Dye-Sensitized Solar Cells to Enhance External Quantum Efficiency in the Ultraviolet
… outlines an improved method incorporating a Lewis acid into a solvothermal reflux reaction (consisting of acetonitrile instead of water) to enable the conversion of D-fructose into 5-HMF in acetonitrile. As a result, this solvothermal method with a Lewis acid catalyst showed fluorescent …
-
Trichloroacetimidates as Alkylating Reagents and Their Application in the Synthesis of Pyrroloindoline Natural Products and Synthesis of Small Molecule Inhibitors of Src Homology 2 Domain- Containing Inositol Phosphatase (SHIP)
… activated by a catalytic amount of a Brønsted or Lewis acid. Work described herein involved taking advantage of the favorable reactivity of trichloroacetimidates to establish several different synthetic protocols, including the application of these reagents in the synthesis of pyrroloindoline …
-
Development and characterization of polyphthalaldehyde for transient applications
… its monomeric component by exposure to heat or acid. Its degradation in response to these stimuli was characterized along with its aging-dependent mechanical properties. Significant effort was invested in on processing (at scale) of cPPA in both solvent/tape casting as well as thermoforming via …
-
Fabrication, analysis, application, and characterization of core-containing microparticles and hydrophilic microfluidic devices produced via the primary- and in situ tertiary-amine catalyzed Michael addition of multifunctional thiols to multifunctional acrylates
… observed to prevent the interaction between the Lewis acid initiator and fumed silica, hence improving the rheological properties of an epoxy system containing the initiator while maintaining the strength of the resulting polymer. Another application involved a novel approach to prepare stable …