Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Leukotriene B4 (LTB4)"”.
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Understanding how neutrophils self-organise their migration to sites of inflammation in vivo
… attractant production, notably of the lipid leukotriene B4 (LTB4). The decision to release attractants at the single-cell level is important and impacts the magnitude of the entire immune response. However, the precise mechanisms triggering this decision remain unclear. In this study, I …
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Neural and Behavioural Consequences of Chronic Inflammation following Spinal Cord Injury
… eicosanoids prostaglandin E2 (PGE2) and leukotriene B4 (LTB4). In addition to such molecular indices, actual changes in each of the outcome variables of interest were assessed. Levels of depression were assessed by questionnaire via the Center for Epidemiological Studies Depression Scale …
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Harnessing Systems Bioengineering Approaches to Study Microbe-Microbe and Host-Microbe Interactions in Health and Disease
… (TNF-α) and interleukin-6 (IL-6), but not leukotriene B4 (LTB4), compared to the infection alone. Our device platform is unique in that the nanoliter well-assisted individual neutrophil trapping enables us to quantify NET release with single-cell precision. Besides, incorporating confined …
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Role of the Leukotriene B4 Metabolic Pathway in Human Pancreatic Cancer
… apoptosis in human pancreatic cancer cells.|Leukotrienes constitute a class of potent biological mediators of inflammation and anaphylaxis. Among them, leukotriene B4(LTB4) is one of the final products of the 5-LOX pathway of arachidonic acid metabolism and it has been widely implicated in …
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Effect of atorvastatin on asthma control and airway inflammation: a randomised controlled trial
… (IL-6), IL-5, IL-8, sICAM-1, TNF-α, leukotriene B4 (LTB4) and high sensitivity C-reactive protein (hsCRP), and blood lymphocyte proliferation. Results At 8 weeks, the change in mean morning PEF, as compared with baseline, did not differ between the atorvastatin and placebo treatment …
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Neutrophil Chemotaxis in Multiple Chemoattractant Gradients
Chemotaxis, the phenomenon in which cells move in response to extracellular chemical gradients, plays a prominent role in the mammalian immune response. During this process, a number of chemical signals, called chemoattractants, are produced at or proximal to sites of infection and diffuse into the …