Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Leukocyte antigens"”.
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Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa
… between the serologically detectable antigens of the HLA-A and B loci and the mixed lymphocyte culture (MLC) reaction is of utmost importance in the understanding of histocompatibility. From the literature it appeared that neither the HLA-A, B genotype nor the MLC reaction is the …
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Control of Hepatitis B and C virus infection in chronic haemodialysis patients
… increased age, male gender, specific human leukocyte antigens, shorter time on a dialysis programme and poor nutritional status. One study has shown an increased response in patients receiving recombinant human erythropoietin and. there is in vitro evidence that nifedipine improves B cell …
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Antibody-omics for biomarker discovery in vaccinology and infectious diseases
… donor-specific antibodies (DSAs) against human leukocyte antigens (HLAs) on the graft, not all transplant recipients experience rejection. Thus, multivariate LASSO-SVM analysis was performed between ABMR+DSA+ and ABMR-DSA+ patients to elucidate the antibody signatures that led to rejection …
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Systems Biology Approach to Identifying Host Interactive Pathways Modulating the Severity of Streptococcal Sepsis
… GAS sepsis. Allelic variations in class II human leukocyte antigens (HLA) contributed significantly to differences in the severity of group A streptococcal sepsis caused by the same virulent strain of the bacteria. HLA class II molecules present streptococcal superantigens (SAgs) to T cells, and …
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Conserved Non-Pocket Interactions Drive The Diversity of Peptide Presentation By Mhc Class I Molecules
… recognition of peptides presented on human leukocyte antigen (HLA) molecules. A thorough understanding of peptide-HLA interactions is needed for improvement of CTL-based immunotherapies. We observed that aspartic acid (D) and glutamic acid (E) at peptide position 4 are highly prevalent in …