Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Leukocyte Elastase"”.
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The synthesis and evaluation of halo and protio enol lactone Pro-Val pseudodipeptides as potential inhibitors of human leukocyte elastase
… inhibitors of the serine protease human leukocyte elastase (HLE). These lactones are incorporated into a Pro-Val pseudodipeptide in order to enhance binding and specificity towards HLE. The synthesis of these compounds proceeded by the cyclization of N-protected forms of the acetylenic …
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HOST DEFENSE PEPTIDES OF THE COAGULATION SYSTEM AND THEIR THERAPEUTIC POTENTIAL
… factor X by proteolytic cleavage with human leukocyte elastase as well as P. aeruginosa elastase. The prototypic peptide RKG25 derived from the core region of the FX protease domain, exhibited multiple biological functions including, antimicrobial, anti-inflammatory and anticoagulant effects. …
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Defining peptide structure with metathesis.
… and serine proteases (α-chymotrypsin, human leukocyte elastase and trypsin). These enzyme assays analyse the efficacy of the inhibitors against the enzymes tested. The potency of the inhibitors against the aforementioned proteases provides an insight into the effect of cyclisation, ring size …
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Risk factors for preperiodontitis in adolescents
Tämän poikkitieteellisen tutkimuksen tarkoituksena on selvittää, kuinka erilaiset potilaskohtaiset riski-indikaattorit voisivat vaikuttaa nuorten alkavan parodontiitin, jota kutsumme preparodontiitiksi, kehittymisen mahdollisuuteen. Tutkimusaineisto koostuu yhteensä 210 suomalaisnuoresta (118 …