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Showing 1 to 2 of 2 for “"Leukemia inhibitory factor receptor"”.

  1. Funktion der Protein-Tyrosin-Phosphatase SHP2 bei der Interleukin 6 vermittelten Akutphase - Genregulation und T-Zell-Migration

    … to mediate SHP2 association to the gp130 receptor subunit and its tyrosine phosphosylation as well as to attenuate IL-6-dependent gene induction. Furthermore, it was shown that repression of gene induction via tyrosine 759 does not require the presence of the SHP2 and STAT recruitment …

    aachen Repository record for Funktion der Protein-Tyrosin-Phosphatase SHP2 bei der Interleukin 6 vermittelten Akutphase - Genregulation und T-Zell-Migration (opens in a new tab)

  2. The Role of LIFR Signaling in Innate Immunity

    … eradication.</p> <p>Here, we uncovered LIFR (leukemia inhibitory factor receptor) restrains low-grade chronic inflammation in the BM by restraining STAT1 signals. LIFR deletion in CD11c-expressing cells resulted in reduced frequency of BM long-term (LT) HSC, increased the frequency of …

    uthsc Repository record for The Role of LIFR Signaling in Innate Immunity (opens in a new tab)