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Showing 1 to 1 of 1 for “"Leukemia, Lymphocytic, Chronic, B-Cell"”.

  1. Potentiating Antibody Therapy by Targeting Complement on Cancer Cells

    … but mAb-induced antigen loss on tumor cells can lead to treatment failure. Loss of cell surface CD20 can occur in the treatment of lymphoid malignancies with anti-CD20 antibodies (mAbs) (eg rituximab, ofatumumab) through trogocytosis. This is a frustrated form of phagocytosis, where the …

    utswmed Repository record for Potentiating Antibody Therapy by Targeting Complement on Cancer Cells (opens in a new tab)