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Showing 1 to 1 of 1 for “"Leucyl-tRNA synthetase (LRS)"”.
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Non-canonical functions of leucyl-tRNA synthetase: Mechanism of cell growth and skeletal myogenesis
… work I have investigated the role of leucyl-tRNA synthetase (LRS) as a leucine sensor regulating mTORC1 activity in cell growth, myogenic differentiation, and skeletal muscle regeneration. Amino acid availability activates signaling by mTORC1. The class III PI-3-kinase Vps34 mediates …