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Showing 1 to 4 of 4 for “"Lethal mutants"”.

  1. Characterization of ftsA conditional lethal mutants shows that FtsA is required at early and late stages of cell division in Streptococcus pneumoniae

    … of S. pneumoniae ftsA thermosensitive (Ts) mutants, obtained by error-prone random PCR, allelic replacement and subsequent screening for ability to grow at 28°C (permissive temperature) but not at 40°C (non permissive temperature). Out of 8000 transformants screened, three, named A19TS, …

    cagliari Repository record for Characterization of ftsA conditional lethal mutants shows that FtsA is required at early and late stages of cell division in Streptococcus pneumoniae (opens in a new tab)

  2. Isolation of Recessive Temperature Sensitive Mutants on the Third Chromosome of <em>Drosophila melanogaster</em>.

    … and more specifically a class of microbial mutants known as conditional lethal mutants. These mutations, which allow survival in a "permissive" environment, but which are lethal under a "restrictive" set of conditions are of three main types --- auxo- trophic, nonsense, and temperature …

    uab Repository record for Isolation of Recessive Temperature Sensitive Mutants on the Third Chromosome of <em>Drosophila melanogaster</em>. (opens in a new tab)

  3. Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii

    … for isolation of temperature-sensitive lethal mutants that are capable of cell growth at a near-wild-type rate, but that exhibit first-cycle failure of cell division (div phenotype). We developed efficient methods for identification of causative mutations by next-generation sequencing of …

    rockefeller Repository record for Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii (opens in a new tab)