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Showing 1 to 13 of 13 for “"Leishmania spp"”.
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Expression of green fluorescent protein (GFP) in Leishmania spp. to identify survival strategies the parasite imposes on the human host
Leishmania protozoa are the etiological agent of human disease known as leishmaniasis. There are three main forms of this disease, whose manifestation depends on a number of factors including the infecting Leishmania species and the immunological status of the individual. Disease development …
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The Use of Geographic Information Systems and Ecological Niche Modeling to Map Transmission Risk for Visceral Leishmaniasis in Bahia, Brazil
Leishmaniasis is a public health problem in Brazil, and despite the control programs in place, Bahia remains one of the states with the highest incidence rates of cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL). This study proposed to develop and evaluate the applicability of …
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New Chemotherapeutic Approaches for the Treatment of Parasitic Protozoan Diseases
… brucei, Trypanosoma cruzi, Toxoplasma gondii, Leishmania spp., and Plasmodium falciparum. These parasites are responsible for African sleeping sickness, South American trypanosomiasis (Chagas' disease), toxoplasmosis, leishmaniasis, and malaria, respectively. The studies contained within this …
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The role of vector-derived microbiota and co-localization in the dissemination of vector transmitted pathogens
Visceral Leishmaniasis poses significant challenges to prophylactic vaccination and treatment strategies due to the ability of Leishmania spp. parasites to disseminate from the initial site of infection in the skin to the internal organs following transmission by the bite of an infected sand fly …
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The role of the flagellum attachment zone in Leishmania mexicana flagellar pocket architecture
Leishmania spp are flagellate protozoan parasites, with a digenetic life cycle, alternating between a mammalian host and insect vector. Within both the host and vector Leishmania adopts different morphologies and cell types, which are adapted to that ecological niche. One of the key architectural …
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Caracterização da resposta imunometabólica frente a infecção por Leishmania amazonensis e Leishmania braziliensis em macrófagos de camundongos BALB/C
INTRODUCTION: Leishmaniasis is a neglected tropical disease caused by protozoa of the genus Leishmania and represents a serious public health problem. These parasites infect cells of the innate immune system, particularly macrophages, and possess the ability to modulate cellular metabolism during …
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Estudo da modulação da migração de células hospedeiras induzida por Leishmania e seu impacto na disseminação do parasito no hospedeiro
Leishmania spp. infect several vertebrate hosts, including humans. The diseases caused by this protozoan, leishmaniasis, can present different clinical manifestations, from localized skin lesions that heal spontaneously, to disseminated skin lesions, mucocutaneous form of the disease, and visceral …
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MONITORING OF LEISHMANIA TARENTOLAE AND LEISHMANIA INFANTUM IN SAND FLIES AND SYNANTHROPIC REPTILES OF NORTHERN ITALY: EMERGING EPIDEMIOLOGICAL SCENARIOS?
… and parasites. Among parasitic infections, leishmaniases, caused by protozoan parasites of the genus Leishmania, rank second only to malaria in terms of mortality. These parasites are transmitted to vertebrate hosts through the bites of infected sand flies (Diptera: Psychodidae: …
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Okuläre Veränderungen bei kutaner und mukokutaner Leishmaniose Untersuchungen in Paraguay
… Veränderungen nach einer Infektion mit Leishmania spp. gedeutet werden. Sie sind rein morphologischer Natur und haben keinerlei Auswirkungen auf den Visus. Es ergaben sich an der Netzhaut keine weiteren Auffälligkeiten, die ursächlich mit der Leishmaniose in Zusammenhang zu bringen …
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Leishmania Infection and Gut Homeostasis in the Sand Fly Lutzomyia longipalpis.
… vectors for the medically important protistan Leishmania spp. It is known that Leishmania develops within the midgut of Phlebotomine sand flies, however, very little research exists pertaining to the immune response and physical effects of Leishmania infection within the sand fly. We have …
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Leishmaniose tegumentar americana no município de Ilhéus- BA: Caracterização de casos humanos e fatores de risco associados
… pesquisados, apresentaram títulos positivos para Leishmania spp., através da RIFI, apenas três animais. O estudo caso-controle revelou que a faixa etária 13 a 44 anos (p = 0,0061; RC = 0,13; IC 95% = 0,076- 0,22) e morar próximo à mata (p = 0,005; RC = 0,09; IC 95% = 0,05- 0,16) constituíram …
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BIOMEDICAL, IMMUNOLOGICALS AND EPIDEMIOLOGICAL STUDIES ON LEISHMANIA
Riassunto della tesi Leishmania tarentolae è un protozoo non patogeno generalmente associato ai rettili, recentemente emerso come modello versatile nella ricerca biotecnologica e biomedica. È caratterizzato da un rapido tasso di crescita, bassi costi di mantenimento e può essere manipolato in …