Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"Left ventricular function"”.
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Surface reconstruction and display of left ventricular function for pet images
… this purpose, a three dimensional object of the left ventricle is formed from an available set of two-dimensional image slices generated by PET. An automatic boundary detection algorithm outlines the object surface and assigns appropriate intensity values to the surface points. The surface is …
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Reproducibility and sensitivity of Doppler echocardiographic indices of left ventricular function during exercise
… most common methods used for the assessment of left ventricular function (LVF) are two-dimensional echocardiography and nuclear ventriculography. Recent technological advances have led to the development of an inexpensive, noninvasive alternative: the stand-alone continuous wave Doppler …
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Left ventricular function after ultra-distance triathlon : response is dependent on the cardiac loading conditions
… evidence to support the hypothesis that altered ventricular loading conditions after the cessation of exercise may cause "cardiac fatigue". The studies that have shown post-exercise "cardiac fatigue" have not controlled for either preload or afterload or both, before and after exercise. These …
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The effect of prolonged exercise and environmental temperature upon left ventricular function and cardiac biomarker release
… as an environmental temperature challenge upon left ventricular (LV) function and cardiac biomarker release. The primary aims were; (1) does repeated exercise bouts mediate a cumulative decrease in LV function and/or increase in cardiac biomarker concentrations; and (2) to examine the impact of …
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Mitochondrial protein acetylation and left ventricular function in a model of hypertrophic cardiomyopathy and heart failure
… fat metabolism, and diastolic and systolic dysfunction. Acetylation correlated strongly with worse heart function, and loss of SIRT3 in the FXN KO mouse resulted in significant decrease in ejection fraction and fractional shortening. Treatment of the FXN/SIRT3 DKO with FXN protein therapy …
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A sequential evaluation of left ventricular function in asymptomatic and symptomatic patients with chronic severe aortic regurgitation
… the unpredictable development of pre-symptomatic left ventricular (LV) dysfunction as a result of prolonged volume overload has resulted in numerous reports attempting to formulate a risk profile for these patients. Although aortic root and LV cineangiography have been the "gold standard" for …
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Effects of exercise training on left ventricular function and exercise capacity in patients with coronary artery disease and varying degrees of left ventricular dysfunction
… patients may have developed chronic asymptomatic left ventricular dysfunction and/or residual myocardial ischaemia, and could become potential candidates for cardiac rehabilitation if exercise training could induce physiological benefits without further deteriorating their condition. Over the last …
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Impact of Glycemic Therapy on Myocardial Sympathetic Neuronal Integrity and Left Ventricular Function in Insulin Resistant Diabetic Rats: Serial Evaluation by 11C-meta-Hydroxyephedrine Positron Emission Tomography
… risk, particularly for diastolic dysfunction. Diabetes is associated with elevated myocardial norepinephrine (NE) content, enhanced sympathetic nervous system (SNS) activity, altered resting heart rate, and depressed heart rate variability. Positron emission tomography (PET) using the …
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Repeated full dose thrombolysis in patients hospitalised with myocardial infarction : safety and efficacy
… arterty, salvage ischaemic myocardium, preserve left ventricular function and save lives. However, thrombolytic drugs are not uniformly effective in securing or maintaining patency of the infarct-related artery.
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The role of myocardial fibrosis and ventricular mechanical dyssynchrony in the pathogenesis and treatment of contractile myocardial dysfunction.
Structural and functional abnormalities of the left ventricle and atrium are important prognostic factors in patients with cardiovascular disease. Dysfunction of the left ventricle in heart failure exposes the left atrium to elevated pressures during diastole, which result in adverse left atrial …
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The Effects of Cocaine and Ecstasy on Cardiac Myocytes and the Intact Myocardium
… affect cellular homeostasis and normal heart function. Cultured cardiac myocytes (H9c2) and New Zealand White rabbits (Oryctolagus cuniculus) were used to measure the responses to various concentrations of cocaine or ecstasy at both the cellular and intact organ system levels. We observed that …
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The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance
Patients with impaired left ventricular function have a poor prognosis. Those with three vessel coronary artery disease who successfully undergo revascularisation have a better outlook but their peri-operative risk is high. Viable myocardium with impaired coronary flow reserve and impaired …
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Studies in right ventricular function: Employing the conductance catheter method for ventricular volume determination
The importance of quantifying right ventricular (RV) function has become clear in recent years. Following adult cardiac surgery right ventricular dysfunction has emerged as a significant cause of morbidity and mortality, particularly after transplantation and during left ventricular (L V) assist …
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Papildomas adenozino vaidmuo mažinant infarkto dydį ir išsaugant kairiojo skilvelio funkciją pacientams, sergantiems ūminiu miokardo infarktu /
… in reducing the infarct size and preserving the left ventricular function in patients with acute myocardial infarction. During the study we examined patients with the left ventricular anterior wall acute myocardial infarction (AMI), when PCI and stenting were used for infarct-related artery (IRA) …
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SIRT1 ACTIVATION IMPROVES HEART FUNCTION THROUGH INHIBITION OF INFLAMMATION IN CHAGAS DISEASE
… inflammatory responses and helped preserve the left ventricular function in chagasic mice. We also found that SRT1720 decreased the proinflammatory differentiation of macrophages in spleen and heart tissue in chronic chagasic mice. SRT1720-treated chagasic mice also significantly reduced in …
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Maternal and cardiac output response to vasopressor therapy during spinal anaesthesia for Caesarean Section in severe preeclampsia
… maternal haemodynamics were measured in the left lateral position, using minimal invasive cardiac output monitoring (LiDCOrapid). A 300 mL colloid preload was then administered. After standard spinal anaesthesia, 20 patients whose mean arterial pressure decreased to a predetermined target …
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Small Therapeutic Peptides: In vitro pharmacokinetics of alpha-carboxyl terminus 11 peptide in rat plasma
… long small peptide that has shown to promote left ventricular function recovery when mouse hearts are perfused with the peptide prior to an ischemia-reperfusion injury. This study investigates the in vitro pharmacokinetics of αCT11 in rat plasma in the presence of protease and phosphatase …
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Prenatal Cocaine Exposure and Cardiac Programming
… size and decreasing postischemic recovery of left ventricular function. Interestingly, the effect of prenatal cocaine exposure on cardiac vulnerability in adult offspring is gender-dependent, with the male heart being more susceptible to increased I/R injury induced by prenatal cocaine …
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Cardiovascular and Inflammatory Consequences of Adverse Childhood Experiences
… types of ACEs (i.e., maltreatment, household dysfunction) and the accumulation of ACEs (i.e., <4 and ≥ 4 different ACEs). First, this thesis sought to identify the effects of adversity on change in arterial stiffness and cardiovagal baroreflex sensitivity (cvBRS) from childhood to young …
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Type-5 Phosphodiesterase Inhibition in the Prevention of Doxorubicin Cardiomyopathy
… Bcl-2 was analyzed by Western blot. Left ventricular function was measured in Langendorff mode. Electrocardiographical analysis measured changes indicative of doxorubicin cardiotoxicity (ST-prolongation). In vitro studies using adult ventricular cardiomyocytes were exposed to …
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