Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"Left Atrium"”.
-
CyberCardia: Patient-specific electrophysiological heart model for assisting left atrium arrhythmia ablation
… the procedure, catheters are inserted into the left atrium to map the atrium geometry and record endocardium electrograms that are then converted into electroanatomical maps to pinpoint the arrhythmia source locations. However, identifying these sources is challenging. The electrograms are …
-
Segmentation and visualization for cardiac ablation procedures
… a method for the automatic delineation of the left atrium in magnetic resonance (MR) images acquired during the procedure. The high anatomical variability of the left atrium shape and of the pulmonary veins that drain into it presents significant difficulties for cardiac ablation. Consequently, …
-
Automatic segmentation of wall structures from cardiac images
… the ventricles from CT images and extract the left atrium from MR images. As applications, the segmentation results are used to facilitate cardiac disease analysis. Specifically, 1. An automatic method is proposed to extract the ventricles from CT images by integrating surface decomposition …
-
Mapping the Characteristics of Atrial Activation Patterns During Atrial Fibrillation
… temporary wire electrodes sutured to the right atrium (RA), the left side of Bachmann’s bundle and posterior left atrium. During AF, a regular rhythm was recorded during four of six episodes from the left atrium, while an irregular rhythm with varying AEG morphologies and CLs was present in the …
-
Multifunctional soft robotic devices and cardiac benchtop models for improved therapy delivery and development
… the development of benchtop models of the left atrium and left atrial appendage that enable device testing, development, and procedural training, and replicate (patho)physiological hemodynamics and motion. Taken together, this thesis research aims to create new therapeutic approaches that …
-
Mitral insufficiency due to ruptured chordae tendineae
… recognizable paradoxical pulsation of the left atrium was present in some of them. At cardiac catheterization a tall left atrial “v” wave with peak pressure as high as or higher than the peak pressure in the pulmonary artery was constantly found.</p><p> In a patient with mitral …
-
The role of myocardial fibrosis and ventricular mechanical dyssynchrony in the pathogenesis and treatment of contractile myocardial dysfunction.
Structural and functional abnormalities of the left ventricle and atrium are important prognostic factors in patients with cardiovascular disease. Dysfunction of the left ventricle in heart failure exposes the left atrium to elevated pressures during diastole, which result in adverse left atrial …
-
A 3-Dimensional In Silico Test Bed for Radiofrequency Ablation Catheter Design Evaluation and Optimization
… arrhythmogenic areas from the rest of the atrium. The standard <em>in vitro</em> evaluation of ablation catheters through lesion studies is a resource intensive effort due to tissue variability and visual measurement methods, necessitating large sample sizes and multiple prototype builds. A …
-
Four-Dimensional Cardiac Magnetic Resonance Analysis in Patients with Atrial Fibrillation
… primarily due to thrombus formation in the left atrium (LA) and left atrial appendage (LAA). while electrophysiological mechanisms of AF are well defined, the LA structural and functional remodelling drives AF onset, persistence, and stroke risk remains incompletely understood. Building on …
-
MODERNIZATION OF THE MOCK CIRCULATORY LOOP: ADVANCED PHYSICAL MODELING, HIGH PERFORMANCE HARDWARE, AND INCORPORATION OF ANATOMICAL MODELS
… pivotal role as the in vitro assessment tool for left heart medical devices. The standard design employed by many research groups dates to the early 1970's, and lacks the acuity needed for the advanced device designs currently being explored. The necessity to update the architecture of this in …
-
Closed mitral valvotomy in pregnancy
… fixed valve area obstructs blood flow from the left atrium to the left ventricle, causing pulmonary congestion and oedema. Careful and regular follow up of these patients is essential, and surgery is indicated if optimal medical management fails. Cardiac surgery duting pregnancy represents a …
-
The Effect of Preload Reduction on Parameters to Evaluate Left Ventricular Diastolic Function
… has been proposed as a new index representing left ventricular(LV) relaxation and related to LV filling pressure. This index has been reported as a preload independent parameter in experimental canine model. The impact of preload on this index, however, has not been studied in human. The …
-
Comparison of echocardiography and computed tomography for characterization of cardiac clots in cats with heart disease
… contrast (SEC or “smoke”) within the left atrium and left auricle. In humans, trans-esophageal echocardiography (TEE) is the gold standard, however computed tomographic angiography (CTA) is becoming more widely used to assess detection of left atrial thrombi precluding the use of …
-
Predicting pulmonary hypertension and outcomes in patients with left heart disease
… chronic infectious diseases, lung diseases and left heart diseases (LHD). It is a global health problem and accounts for a substantial portion of cardiovascular disease. PH due to LHD (PH-LHD) is credited to be the most common form of PH worldwide and is associated with adverse outcomes. …
-
Optimisation of Surgical Timing in Rheumatic Mitral Valve Disease
… Chapter 5 demonstrates the potential role of the left atrium in the management of rheumatic mitral valve disease. It finds that left atrial ejection fraction is the strongest and most reliable predictor for developing a guideline indication for valve intervention in the subsequent two-years. …
-
Age-associated changes to calcium handling proteins across the whole heart
… pumps (PMCA) were analysed in the SA node, right atrium, left atrium, left ventricle and right ventricle.The effect of ageing of the SA node was assessed via recordings of intrinsic heart rate in response to isoprenaline, a β-adrenergic stimulator, and nifedipine. With age response to isoprenaline …
-
Development and Application of Low-Order Computational Models of the Left Ventricle
… work is to develop theoretical models for left ventricle (LV) dynamics that allow rapid estimation of myocardial stiffness and contractility from echocardiogram data. To reduce the computational complexity of this inverse problem, we represent LV deformation in terms of a limited number of …
-
Universal Atrial Coordinate (UAC) for Wall Motion Deep Learning
… increases stroke risk through altered left atrial (LA) wall motion and blood stagnation in the left atrial appendage (LAA). Standard scores like CHA₂DS₂-VASc overlook patient-specific motion patterns, while AF's episodic nature and anatomical variability hinder consistent analysis. This …