Global ETD Search
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Showing 1 to 3 of 3 for “"Lectins, C-Type"”.
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Molecular Basis of Peptidoglycan Recognition by a Bactericidal Gut Lectin
… RegIII proteins are novel in that they are C-type lectins that directly kill Gram-positive bacteria and thus play a vital role in antimicrobial protection of the mammalian gut. RegIII proteins bind their bacterial targets via interactions with cell wall peptidoglycan, but lack the canonical …
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The Ligand and Function of the RegIII Family of Bactericidal C-Type Lectins
… This screen revealed that expression of two C-type lectins, RegIIIbeta and RegIIIgamma , is strongly induced following intestinal colonization with resident microbes. Two features suggested that members of the RegIII family may have microbicidal functions. First, they are C-type lectin family …
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Biophysical Studies of Pathogen Recognition by C-Type Lectins
C-type lectins are a prominent class of pathogen recognition receptors in the innate immune system. The three pathogen recognition lectins studied in this thesis are the mannose binding protein (MBP), the dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN) and the dendritic cell-specific …