Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Lateral fluid percussion"”.
-
Iterative learning control for improved tracking of fluid percussion injury device
… acting on the head during such TBI events. Lateral Fluid Percussion (FPI) brain injury is one of the most commonly used and well-characterized experimental models of TBI. A Fluid Percussion Injury (FPI) device in the laboratory is used to replicate the injury but does not execute the desired …
-
Onset of Insulin Resistance in Hippocampal Synapses After Traumatic Brain Injury: Relevance to Alzheimer’s disease and Therapeutic Implications
… I used male Sprague-Dawley rats that underwent a lateral fluid percussion injury (FPI) at acute (2 and 7 days post-injury), intermediate (28 days post-injury), and chronic (3 months post-injury) time-points to investigate whether decreased insulin responsiveness in TBI animals is playing a role in …
-
FEAR EXTINCTION AND INFRALIMBIC CORTEX IMPAIRMENT AFTER MILD TRAUMATIC BRAIN INJURY
… model of TBI. Our results demonstrate that mild lateral fluid percussion injury (LFPI) significantly impairs fear extinction memory, as evidenced by an elevated cued-fear response during extinction testing 10 days post-injury. Field potential recordings revealed decreased activation of the IL …
-
Modeling subconcussive and cumulative subconcussive impacts using a lateral fluid percusion injury device
… and scientific community. This study used a lateral fluid percussion injury (lFPI) to model a subconcussive insult; specifically, to test the hypothesis that an initial subconcussive insult will not lead to any significant detectable levels of behavioral or cellular damage, yet cumulative …
-
Investigating the cerebral/pulmonary axis following traumatic brain injury in a preclinical model
… both the brain and lung following TBI using the lateral fluid percussion injury (FPI) in an in-vivo murine model. In the murine FPI model, alongside cerebral inflammation (associated with neuronal damage and the infiltration of inflammatory cells), there is significant neutrophil accumulation …
-
Investigation of chemokine expression and modulation following traumatic brain injury
… expression in-vivo I established the rat lateral fluid percussion injury (LFPI) model of TBI and measured MIP-2/CXCL2 and MCP-1/CCL2 expression in the brain following injury. Inhibition of this expression by dexamethasone and FK506 was then investigated. To identify the cellular source of …