Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Lateral flow assays"”.
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Rational hydrogel design for point-of-care bioassays
… technologies are largely centered on lateral flow assays. Hydrogel microparticles have been used extensively for bioassays due to their nonfouling nature and ability to be functionalized with different types of biomolecules. Here, we use polyethylene glycol hydrogel particles to …
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Antibiotic Resistance Genes in Marquette County Michigan's Wastewater
… for carbapenemase expression using CARBA-5 NG lateral flow assays, where KPC and OXA-48 screened positive. We opted to use 16Ss rRNA sequencing and MALDI-TOF MS to identify the bacteria expressing carbapenemases, and we identified three bacteria that either harbor or exhibit strong resistance …
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Improved Detection of Gold Nanoparticle Labels for Paper-Based Analytics
… improved quantified detection of labels used in lateral flow assays. Limits of detection were characterized for: (a) optical approaches, i.e., unaided eye, mobile electronic device camera images and microscope images with image analysis software developed through this thesis, and (b) a …
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Noninvasive disease diagnostics using engineered synthetic urinary biomarkers
… compatible with clinical ELISA and paper-based lateral flow assays. These detection techniques enable simple and inexpensive quantification of our synthetic disease reporters by ensuring compatibility with existing diagnostic resources and infrastructure. To demonstrate our platform's …
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Development of Au-Pt Nanoflowers as Nanoenzyme for Highly Sensitive Immunoassay: Application to the Detection of Melioidosis Biomarker
… study, we present a core shell gold-platinum nanoflowers (Au-Pt NFs) as signal labels in immunoassays for sensitive detection of capsular polysaccharides (CPS) expressed on the cell envelopes of Burkholderia pseudomallei causing Melioidosis, an infectious disease of global health concern. …
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Aptamers that bind SARS-CoV-2 spike protein for COVID-19 rapid diagnostics and therapeutics
… and affinity (< 80 nM). Through binding assays and high resolution cryo-EM, we demonstrate that SNAP1 (SARS-CoV-2 spike protein N-terminal domain-binding aptamer 1) binds to the S N-terminal domain. We applied SNAP1 in lateral flow assays (LFAs) and ELISAs to detect UV-inactivated …
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Preparation and evaluation of polymer microspheres for enhanced lateral flow immunoassay: the case study for malaria
… be developed as viable detection reagents for lateral flow technology. This body of work outlines the development of this new high capacity polymer microsphere technology for suitability to flow on lateral flow membranes, and highly specific biomarker detection for immunoassay development. …
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Development of gold nanoparticles based lateral flow assay for detection of food and water-borne pathogens
… The use of gold nanoparticles (AuNPs)-based lateral flow assay (LFA) for the detection of these pathogens is gaining traction among researchers as an alternative to conventional methods for on-site testing in places where there is no proper infrastructure, particularly low-resourced areas. …