Global ETD Search
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Showing 1 to 1 of 1 for “"Late-onset Responses"”.
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Bayesian Adaptive Designs For Early Phase Clinical Trials
… and <strong>(3)</strong> incorporating missing late-onset responses to make an early stopping decision.</p> <p>Treating patients with novel biological agents is becoming a leading trend in oncology. Unlike cytotoxic agents, for which toxicity and efficacy monotonically increase with dose, …