Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 14 of 14 for “"Langmuir Trough"”.
-
Biophysical Characterization of Nanoparticle Interactions with Lung Surfactant Models for Enhanced Pulmonary Drug Delivery
… therapy. Surface activity was measured using a Langmuir trough with two Teflon barriers to mimic the air-water interface and compress the surfactant monolayer. Imaging of the monolayer was conducted with Brewster angle microscopy to visualize changes in the organization of the surfactant models. …
-
Biophysical Insights into Lipid Oxidation Effects on Membrane Self-Organization and Enzymatic Catalysis Under Extreme Conditions
… (AAPH), and observations from the Langmuir trough technique revealed a consistent increase in relative molecular area for oxidized unsaturated lipids. Additionally, the sta- bility plots remained unchanged, although shifted towards larger molecular areas, sug- gesting a direct …
-
Biochemical studies of the tear film in humans and rabbits
… using the vapour pressure osmometer, and the Langmuir trough, respectively. Compared to human tears, rabbit tears had a higher osmolality and demonstrated different tear surfactant properties, which indicates the different biochemical composition of tears from the two species. In this thesis, …
-
Development of new tools to study drug-lipid interactions and their application to investigating amphotericin b's association with model cell membranes
… sterol-containing floating lipid monolayers on a Langmuir trough. Electrochemical control over the adsorbed monolayer allowed the defectiveness of the layer to be varied and the interaction of AmB with both well-ordered and defective monolayers characterized. Measurements of monolayer capacitance …
-
A Mesoscale Dynamics study of the phases in surfactant-water ternary systems
… simulations, were found to be important through Langmuir trough investigations adding ionic and nonionic anaesthetics to non-ionic surfactant and ionic lipid monolayers, as ionic monolayer-anaesthetic combinations showed a larger increase in surface pressure compared to the non-ionic …
-
Synthetic analogues of protein-lipid complexes
… changes of DLPC upon associating with PSMA. The Langmuir Trough technique and surface tension measurement were used to explore the association behaviour of PSMA both at the interface and in the bulk of solution, as well as its interaction with DLPC membranes. The ultimate aim of this study was to …
-
A study of zwitterionic adducts of TCNQ.
… Chapter 3 gives a general introduction to Langmuir-Blodgett (LB) films starting once again from a historical perspective. The molecular requirements of suitable materials together with pressure/area per molecule measurements and the deposition process are described. The various methods …
-
Preparation of anisotropic microparticles and their behaviour at liquid interfaces
… compression and expansion experiments in a Langmuir trough has important implications on particle stabilisation of foams and emulsions. This has been known for some time with regards to spherical particles. In this investigation, we have studied the role of non- spherical particles at the …
-
Integrating novel rheological tools with microscopy to characterize viscoelastic properties of complex materials
… challenging. We developed a miniaturized radial Langmuir trough to study complex fluid-fluid interfaces under purely dilatation deformations that operates in tandem with a conventional inverted microscope for simultaneous interfacial visualization. In our findings, we were able to evaluate …
-
Janus Particles at the Air-Water Interface: Single particle behavior, particle-laden interfaces, and implications for self-assembly
… interfaces with various wetting properties on a Langmuir trough. From these studies we find that for Janus particles below a certain degree of amphiphilicity, almost half of the particles are observed to be in non-equilibrium orientations at the air-water interface. Particle orientation becomes …
-
Synthesis and performance of novel supramolecular tools for single-particle cryogenic electron microscopy and drug and gene delivery
… of graphene-oxide and monolayer fabrication on a Langmuir trough. These monolayers were characterized by AFM, SEM, and evaluated for specific capture of his-tagged protein targets. These materials were also used to capture his6-GroEL from clarified cell lysates and used to generate a cryo-EM …
-
A Study of the Membrane Binding Properties of the Matrix Protein from Human Respiratory Syncytial Virus
… matrix proteins. Experiments performed on a Langmuir trough revealed that the M protein partitions into phospholipid monolayers, regardless of whether the lipid head group is phosphocholine or phosphoethanolamine. It interacts differently with monolayers containing sphingomyelin, which in …
-
Adsorption Kinetics and Phase Behavior of Particles Adsorbed at an Interface
… similar to those used in the derivation of the Langmuir-Szyszkowski equation of state for localized adsorption. This work aims to predict the adsorption kinetics and phase behavior of a system composed of many hard-core particles based on kinetic arguments and the Gibbs adsorption isotherm. To …