Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Langerhans cells"”.
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Characterization of human foreskin Langerhans cells
… a foreskin (FS) that harbors different immune cells that are HIV target cells such as CD4+ macrophages, T, Langerhans (LCs), and dendritic cells (DCs). However, there have been different reports on whether the inner FS or outer FS has more HIV target cells. While LCs have been implicated in HIV …
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Dynamic Behaviors of Langerhans Cells In Situ
The file named "wardbrant.pdf" is the primary dissertation file. Supplemental videos (Movies 1-27) are also provided (in RealPlayer Video format), and more information about each video is available in the file named "Legend.pdf".
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Defining interactions between Mycobacterium leprae and Langerhans cells
… of the intricate interactions with innate immune cells has made advances in some cell subsets but is limited in others leaving an incomplete picture of the disease. These gaps limit advances in disease management. M. leprae is an obligate, intracellular pathogen that grows preferentially between …
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Investigating lesions of Langerhans cells and their role in Lymphoproliferative diseases
Langerhan’s cells (LCs) are the immune sentinels of the skin, sampling the cutaneous microenvironment and presenting captured antigen to T cells. A sheet-like proliferation of LCs is termed Langerhan’s cell histiocytosis (LCH), an enigmatic and poorly understood disorder with a widely varied …
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ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΩΝ ΚΥΤΤΑΡΩΝ LANGERHANS ΣΤΗΝ ΕΠΟΥΛΩΣΗ ΤΡΑΥΜΑΤΟΣ. ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ ΣΕ ΛΕΥΚΟΥΣ ΕΠΙΜΥΣ
LANGERHANS CELLS ARE EPIDERMAL CELLS AND WERE DESCRIBED BY P. LANGERHANS IN 1868. FOR SOME TIME AFTER THEIR DISCOVERY, THEIR ORIGIN, NATURE AND FUNCTIONS REMAINED UNKNOWN. THE AIM OF THIS STUDY WAS TO DETERMINE (1) THE QUANTITATIVE DISTRIBUTION OF LANGERHANS CELLS DURING THE HEALING PROCESS OF …
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Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
… collagen type IV, laminin, elastin, fibronectin,Langerhans cells and VEGFR-3. Murine markers included collagen type IV, laminin,fibronectin, Langerhans cells and VEGFR-2. Staining intensities were quantified and statistically analysed using one-way ANOVA with subsequent Friedman’s test for …
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Ex-vivo Untersuchungen zur Arzneimittelwirkung topischer Tacrolimus (FK-506) Anwendung auf epidermale dendritische Zellen in läsionaler Haut bei Patienten mit atopischem Ekzem
… of epidermal antigen-presenting dendritic cells in atopic dermatitis. BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease in which antigen-presenting epidermal dendritic cells (DCs), ie, Langerhans cells and the so-called inflammatory dendritic epidermal cells (IDECs) …
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Layer-by-layer coated microneedles for cancer immunotherapy
… vaccines to activate the potent epidermal Langerhans cells and dermal dendritic cells. The drug was incorporated as a releasable multilayer coating on the microneedle surface constructed with alternating absorption of oppositely charged species including protein or nucleic acid drugs and …
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Degradable polymeric nano-films and particles as delivery platforms for vaccines and immunotherapeutics
… the protein by skin-resident antigen-presenting cells (Langerhans cells), and transport of the antigen to the skin-draining lymph nodes. Dual incorporation of OVA and CpG oligonucleotides into the nanolayers of LbL films enabled dual release of the antigen and adjuvant with distinct kinetics for …
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Τα κύτταρα Langerhans στο ακανθοκυτταρικό καρκίνωμα του στόματος: ανοσοϊστοχημική μελέτη με την S-100 πρωτεΐνη
… ORAL SQUAMUS CELL CARCINOMA FOR THE PRESENCE OF LANGERHANS CELLS (L.C) IN FORMALIN-FIXED, PARAFIN-EMBEDED MATERIAL, BY USING S-100 PROTEIN IN THE INDIRECT IMMUNOPEROXIDASE METHOD. ITWAS FOUND THAT: 1) S-100 PROTEIN IS A GOOD MARKER FOR THE IMMUNOHISTOCHEMICAL IDENTIFICATION OF L.C IN ORAL SQUAMUS …
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Exposure of 3D organotypic vaginal tissues to semen induces expression of the chemokine MCP-1, but does not alter tissue integrity
… normal epithelium in addition of fibroblasts and Langerhans cells. We hypothesized that semen is not toxic to the EpiVaginalTM tissue, which is morphologically similar to native vaginal mucosa, and does not induce a proinflammatory response. We found that semen and/or seminal plasma did not induce …
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Intravital Imaging of Dynamic Behaviors of Leukocytes in UVB-induced Skin Inflammation
… irradiation diminishes surface densities of Langerhans cells (LCs) in the epidermis of the skin. Other leukocytes, such as neutrophils and macrophages, are recruited to the irradiated sites due to chemo-attracting factors released from the altered microenvironment. However, there is little …
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Polymer substrates with microneedles for epidermis injection
… externally through the epidermis. In the latter, Langerhans cells can be utilized for activating the immune system by releasing antigenes. Aims of this thesis show the effects of polymer microneedle substrates with methods for constructing the substrate arrays that are flexible adherent to the …
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The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells
… and possible mortality. Viral entry into cells requires the co-ordinated action of at least four HSV-1 envelope glycoproteins: gB, gD and the heterodimer gHgL. Dendritic cells (DC) are the most potent antigen presenting cells and are likely to encounter the virus early after entry into the …
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Histopathologic Features in Vitiligo
… staining. However, S-100 protein positive cells were detected 100% of vitiligo skin and their average number 175.36/mm2, which is much higher than those of NKI/beteb and MART-1 staining. Especially, S-100 protein positive cells were increased in inflammatory vitiligo than noninflammatory …
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Chemoprevention of Familial Melanoma
… an immune response against distant pigment cells. Cytotoxic experiments reveal that similar to 4-TBP, MBEH induces specific melanocyte death. To compare death pathways initiated by 4-TBP and MBEH, classical apoptotic hallmarks were evaluated in treated melanocytes. MBEH induced cell death …
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Outcomes of children with biopsy-proven Langerhans cell histiocytosis (LCH) treated at the Red Cross War Memorial Children's Hospital from 1998 – 2017
Background: Langerhans Cell Histiocytosis (LCH) is a rare histiocytic disorder characterised by the infiltration of a single organ or multiple organs by cells phenotypically similar to Langerhans cells. The number and type of systems involved affect the outcome and the longer the maintenance …
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Investigating the susceptibility of foreskin myeloid cells to ex vivo HIV infection
… populations of innate and adaptive immune cells, that are permissive to HIV infection5–8. In support of this, medical male circumcision (MMC), has been reported to confer up to 60 % risk reduction in HIV acquisition9–17. Most studies have focused on investigating blood lymphoid immune cells …
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Immunotoxicity of Dermal Permethrin and Cis-Urocanic Acid: Effects of Chemical Mixtures in Environmental Health
… and inhibited antibody production by splenic B cells. cUCA worsened the negative effect of permethrin on both thymic weight and cellularity, and depressed splenocyte blastogenesis, hydrogen peroxide production, and antibody production. Five-day exposure to either cUCA or permethrin also caused …
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