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Showing 1 to 8 of 8 for “"Langerhans cell"”.
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Σύγχρονα δεδομένα για τη διάγνωση και θεραπεία της ιστιοκύττωσης Langerhans / Current concepts for the diagnosis and management of Langerhans cell histiocytosis
Η ιστιοκύττωση Langerhans αποτελεί σπάνια ιστιοκυτταρική διαταραχή με ιδιαίτερα ετερογενή κλινική εικόνα, η οποία μπορεί να κυμαίνεται από εντοπισμένη, αυτοϊώμενη νόσο έως πολυσυστηματική μορφή με σοβαρή νοσηρότητα και αυξημένη θνητότητα. Η νόσος χαρακτηρίζεται από κλωνικό πολλαπλασιασμό …
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Outcomes of children with biopsy-proven Langerhans cell histiocytosis (LCH) treated at the Red Cross War Memorial Children's Hospital from 1998 – 2017
Background: Langerhans Cell Histiocytosis (LCH) is a rare histiocytic disorder characterised by the infiltration of a single organ or multiple organs by cells phenotypically similar to Langerhans cells. The number and type of systems involved affect the outcome and the longer the maintenance …
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Vip And Host Immunity
… anti-inflamamtory TLRs in macrophages and Langerhans (XS52) cells. Exogenous VIP also decreased Langerhans cell number in the infected cornea.</p> <p>Furthermore, we used VIP-/- mice to asses whether VIP is required for expression of growth factors and their receptors in normal and infected …
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Deficiência de arginina-vasopressina (diabetes insipidus central) como primeira manifestação de histiocitose de células de Langerhans: relato de caso
Introduction: Langerhans cell histiocytosis (LCH) is a rare clonal neoplasm of the mononuclear phagocyte system characterized by proliferation of CD1a⁺/Langerin⁺ myeloid dendritic cells and activating mutations in the MAPK/ERK pathway (such as BRAF V600E and MAP2K1). Involvement of the …
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Human immunodeficiency virus (HIV) and Human papillomavirus (HPV) infection and cell cycle regulators in preinvasive lesions and invasive carcinomas of the anus
… The majority of these carcinomas are squamous cell carcinomas and are associated with high risk-HPV infection. HIV infection appears to interact synergistically with high risk-HPV in the development of squamous cell carcinoma at this site. Aims and objectives: To review the pathology of anal …
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Immunogeneic Cell Populations of the Skin
Dendritic cells (DCs), a hematopoietic cell type belonging to the sub-group of cells called antigen presenting cells (APCs), inhabit a central role in innate and adaptive immunity. Although the DC family is very heterogeneous, all members share unique features. Most importantly, DCs can stimulate …
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New Roles of the Transcription Factor NKX6.1 in Beta Cell Biology
Pancreatic islet beta cells play a critical role in the maintenance of metabolic fuel homeostasis. Type 1 diabetes results from autoimmune destruction of the beta cells, whereas type 2 diabetes involves loss of beta cell function, particularly glucose-stimulated insulin secretion (GSIS), and a …
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Novel Roles of Gastrin and Cholecystokinin in Islet Beta Cell Proliferation
… share a common theme: an insufficient beta cell mass to maintain glucose homeostasis. In Type 1 diabetes this deficiency arises from autoimmune destruction of the beta cells. In the latter stages of Type 2 diabetes, there is a precipitous drop in beta cell mass, resulting from the …